Polypeptides having L-asparaginase activity

Details Polypeptides having L-asparaginase activity Polypeptides having L-asparaginase activity

1998-11-19

2000-10-31

Nashed, Nashaat T.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

435325, 43525233, 4353201, 536 232, 536 231, C07H 2104, C12N 982, C12N 120, C12N 500

Patent

active

061401013

ABSTRACT:
Disclosed are polypeptides which originate from mammal, having L-asparaginase activity. The polypeptides are easily prepared by applying recombinant DNA techniques to DNAs encoding the polypeptides and they exert satisfactory effects in the treatment and/or the prevention for diseases caused by tumor cells dependent on L-asparagine, and cause no substantial serious side effects even when administered to humans in relatively-high dose.

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