Polypeptides having kinase activity, their preparation and use

Details Polypeptides having kinase activity, their preparation and use Polypeptides having kinase activity, their preparation and use

1997-01-09

1998-12-08

Grimes, Eric

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Insect cell, per se

4353201, 435325, 536 232, 536 243, C12N 510, C12N 516, C12N 1554, C12N 1563

Patent

active

058468242

ABSTRACT:
This invention relates to new polypeptides which exhibit kinase activity or, more specifically, which show phosphoinositide (PI) 3-kinase activity. Such polypeptides are involved in pathways responsible for cellular growth and differentiation. An isolated polypeptide which possesses PI3-kinase activity when produced by recombinant production in insect cells is disclosed.

REFERENCES:
Otsu et al., Cell 65:91-104, 1991.

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