Polypeptides having dipeptidyl aminopeptidase activity and...

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Enzymatic production of a protein or polypeptide

Reexamination Certificate

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C435S212000, C536S023200

Reexamination Certificate

active

07098001

ABSTRACT:
The present invention relates to isolated polypeptides having dipeptidyl aminopeptidase activity and isolated nucleic acid sequences encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing and using the polypeptides.

REFERENCES:
patent: WO 96/28542 (1996-09-01), None
patent: WO 97/43910 (1997-11-01), None
Tachi et al., “An X-Prolyl Dipeptidyl-Aminopeptidase FromAspergillus oryzae”, Phytochemistry vol. 31, No. 11, pp. 3707-3709, 1992.
Beauvais et al., “Biochemical and Antigenic Characterization of a New Dipeptidyl-Peptidase Isolated FromAspergillys fumigatus” Journal of Biological Chemistry 272 (10), 1997, pp. 6238-6244.
Heymann et al., “Complementary Action of Dipeptidyl Peptidase IV and Aminopeptidase M In The Digestion of β-Casein”, J. Dairy Res 53, 1986, pp. 229-236.
Chemical Abstracts, vol. 124, No. 21, May 20, 1996 (XP-002051874).
Database WPI, Section Ch, Week 9527, May 9, 1995 (XP-002047737).
Database WPI, Section Ch, Week 9710, (XP-002076623).
Beauvais et al., “Dipeptidyl-Peptidase IV Secreted byAspergillus fumigatus, A Fungus Pathogenic to Humans” Infection and Immunity, vol. 65, No. 8, Aug. 1997, pp. 3042-3047.
EMBL/GENBANK Databases, Accession No. AJ002369, Sequence Reference No. A0DPPIV, Mar. 2, 1998 (XP-002076626).

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