Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2007-10-09
2007-10-09
Chan, Christina (Department: 1644)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007240, C530S350000, C530S387100, C530S388220
Reexamination Certificate
active
11483991
ABSTRACT:
The invention relates to polypeptides having a triggering NK activity and an amino acid sequence that is at least 80% identical over its entire length to the polypeptide having SEQ ID NO: 1, and any immunogenic fragments thereof, as well as to the polyclonal and monoclonal antibodies directed against said polypeptides, and immuno-reactive fragments thereof. Application for detecting NK cells in a sample, for their removal from a sample or for enrichment of NK cells, and for NK cell natural cytotoxicity regulation.
REFERENCES:
Vitale Massimo et al. “Identification of NKp80, a Novel Triggering Molecule Expressed by Human NK Cells”European Journal of Immunology, Jan. 2001, pp. 233-242, vol. 31, No. 1.
Roda-Navarro et al. “Human KLRFI, a Novel Member of the Killer Cell Lectin-Like Receptor Gene Family: Molecular Characterization, Genomic Structure, Physical Mapping to the NK Gene Complex and Expression Analysis”European Journal of Immunology, Feb. 2000, pp. 568-576, vol. 30, No. 2, XP001062417.
Database EMBL ′Online!, HS1225660 Ac No. AA424848, May 24, 1997, Hillier et al. “zw03b04.s1 Soares—NhHMPu—S1Homo sapienscDNA Clone Image: 768175”, XP002192078.
Database EMBL ′Online!, HS16432 Ac No. T60164, Mar. 4, 1995, Hillier et al. “yc22d06.s1 Stratagene Lung (#937210)Homo sapienscDNA Clone Image: 81419”, XP002192079.
Moretta et al. “Natural Cytotoxicity Receptors That Trigger Human NK-Cell-Mediated Cytolysis”Immunology Today, May 2000, pp. 228-234, vol. 21, No. 5, Elsevier Publications, Cambridge, GB.
Biassoni Roberto
Bottino Cristina
Moretta Alessandro
Chan Christina
Huynh Phuong
Innate Pharma S.A.
Saliwanchik Lloyd & Saliwanchik
Universita Di Genova
LandOfFree
Polypeptides having a triggering NK activity and biological... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Polypeptides having a triggering NK activity and biological..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polypeptides having a triggering NK activity and biological... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3889332