Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1994-06-28
1996-12-03
Elliott, George C.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C07K 1482, C07K 14435
Patent
active
055809588
ABSTRACT:
The invention provides a purified polypeptide having substantially the same amino acid sequence and activity as the protein having the amino acid sequence of FIG. 1 , or a characteristic fragment thereof. The polypeptide is a transcriptional activator. Nucleic acids encoding the polypeptide and uses are also provided.
REFERENCES:
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Boulukos et al Embo Journal, vol. 7 No. 3, 697-705 1988.
Klemsz et al Cell vol. 61, 113-124, 1990.
Shaw et al, Sci. 241:202-205 (1988).
Moreau-Gachelin et al., The putative oncogene Spi-1: murine chromosomal localization and transcriptional activation in murine acute erythroleukemias Nature 331:277-284 (1989).
Guarente, Leonard. Cell. 52:303-305 (1988).
Karim, F. D. et al. Genes & Development. 4(9):1451-1453 (1990).
Celada Antonio
Klemsz Michael J.
Maki Richard A.
McKercher Scott R.
Elliott George C.
La Jolla Cancer Research Foundation
Priebe Scott David
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