Polypeptides comprising IL-6 ligand binding receptor domains

Details Polypeptides comprising IL-6 ligand binding receptor domains Polypeptides comprising IL-6 ligand binding receptor domains

2006-12-05

2006-12-05

Mertz, Prema (Department: 1646)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C530S323000, C530S324000, C530S325000, C530S326000

Reexamination Certificate

active

07144986

ABSTRACT:
The present invention provides, among other things, a polypeptide, and a pharmaceutically acceptable salt thereof, that inhibits the binding of IL-6 ligand with IL-6 receptor under physiological conditions, a nucleic acid that encodes such a polypeptide and can be expressed in a cell, a nucleic acid that comprises or encodes an antisense nucleic acid molecule or a ribozyme that is specific for such a polypeptide, an antibody that is specific to such a polypeptide, an anti-antibody thereto, a composition comprising such a polypeptide, nucleic acid, antibody or an anti-body and a carrier therefor, a composition comprising a solid support matrix to which is attached an above-described polypeptide or an anti-antibody to a specified polypeptide sequence, a method of prophylactically or therapeutically inhibiting IL-6 signaling in a mammal in need thereof, a mammal in need thereof, and a method of removing IL-6 ligand from a bodily fluid of an animal.

REFERENCES:
patent: 5132403 (1992-07-01), Kishimoto
patent: 5171837 (1992-12-01), Tanihara et al.
patent: 5171840 (1992-12-01), Kishimoto
patent: 5210075 (1993-05-01), Scholz et al.
patent: 5216128 (1993-06-01), Novick et al.
patent: 5324483 (1994-06-01), Cody et al.
patent: 5470952 (1995-11-01), Stahl et al.
patent: 5585275 (1996-12-01), Hudson et al.
patent: 5591646 (1997-01-01), Hudson et al.
patent: 5591827 (1997-01-01), Brakenhoff et al.
patent: 5639455 (1997-06-01), Shimamura et al.
patent: 5670373 (1997-09-01), Kishimoto
patent: 5681723 (1997-10-01), Ciliberto et al.
patent: 5702672 (1997-12-01), DeWitt et al.
patent: 5712383 (1998-01-01), Sheridan et al.
patent: 5723120 (1998-03-01), Brakenhoff et al.
patent: 5789552 (1998-08-01), Savino et al.
patent: 5792850 (1998-08-01), Baumgartner et al.
patent: 5814700 (1998-09-01), Brennan
patent: 5817790 (1998-10-01), Tsuchiya et al.
patent: 5837858 (1998-11-01), Brennan
patent: 5847105 (1998-12-01), Baldeschwieler et al.
patent: 5849283 (1998-12-01), Ciliberto et al.
patent: 5869644 (1999-02-01), Shortle et al.
patent: 5869696 (1999-02-01), Reddy et al.
patent: 5874165 (1999-02-01), Drumheller
patent: 5886104 (1999-03-01), Pedersen et al.
patent: 6031074 (2000-02-01), Saxinger
patent: 6664374 (2003-12-01), Saxinger

Affiliated with

Also associated with

Rating

Polypeptides comprising IL-6 ligand binding receptor domains does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Polypeptides comprising IL-6 ligand binding receptor domains, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polypeptides comprising IL-6 ligand binding receptor domains will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3663808