Polypeptides comprising domains of the GAX protein implicated in

Details Polypeptides comprising domains of the GAX protein implicated in Polypeptides comprising domains of the GAX protein implicated in

1997-10-15

2000-09-19

Schwartzman, Robert A.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

530324, 530350, C07K 1447, G01N 3353

Patent

active

061210056

ABSTRACT:
This invention pertains to polynucleotides comprising GAX domains involved in GAX biological activity. It may pertain, notably, to domains involved in the interaction of GAX with other molecules or domains that are responsible for biological activity. The invention also pertains to chimeric molecules comprising a GAX functional domain. It also pertains to the use of GAX to repress gene expression, as well as the use of compounds that inhibit GAX interaction with certain cellular partners to modulate GAX activity. It also pertains to a method for screening and/or identifying GAX cellular partners.

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