Polypeptides and production thereof

Chemistry: molecular biology and microbiology – Spore forming or isolating process

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435 6951, 4352523, 43525233, 4353251, 536 27, 935 10, C12N 1500, C12N 1519, C12N 1570

Patent

active

051570041

ABSTRACT:
The present invention provides a novel polypeptide which shows higher IFN-.gamma. activity than intact IFN-.gamma. and a method of producing the same.
The polypeptides not only possesses a remarkable antiviral activity, antitumor activity, immunopotentiating activity etc. but also is highly stable, therefore, it can be used advantageously as pharmaceuticals etc.

REFERENCES:
patent: 4832959 (1989-05-01), Engles
patent: 4855238 (1989-08-01), Gray et al.
Gray et al., Nature 298: 859 (1982).
Capon et al., in the Third Annual International Congress for Interferon Research, Miami, Fla., Abstract (1982).
Roberts et al., Proc. Natl. Acad. Sci. USA 76: 760 (1979).

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