Polypeptides and methods for making the same

Details Polypeptides and methods for making the same Polypeptides and methods for making the same

2004-02-27

2009-08-25

Ouspenski, Ilia (Department: 1644)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C514S012200

Reexamination Certificate

active

07579437

ABSTRACT:
An isolated protein having at least 90% homology with the dimeric protein having the following amino acid sequence (I) with the proviso that at the C-terminal end of the monomeric forms, 2 to 10 amino acid distance from Z2, a Cys is present for forming the dimeric or multimeric protein, Z1is a signal peptide for protein transport to the ER and/or through the plasma membrane or NH2or a derivative of an NH2group such as an alkylated, or acylated derivative, or polyethylene glycol (PEG) moiety, Z2is an amino acid residue with up to 20, in particular 10 or 8 amino acids which are selected of substantially non-hydrophobic naturally occurring amino acids or COOZ3wherein Z3is hydrogen, a metal ion, a hydrocarbon moiety substituted or non-substituted with heteroatoms.

REFERENCES:
patent: 5851795 (1998-12-01), Linsley et al.
patent: 5885796 (1999-03-01), Linsley et al.
patent: 6812339 (2004-11-01), Venter et al.
patent: 6875904 (2005-04-01), Liu et al.
patent: WO 95/01994 (1995-01-01), None
patent: WO 97/47732 (1997-12-01), None
Attwood T., Science 2000; 290:471-473.
Skolnick et al., Trends in Biotech. 2000; 18(1):34-39.
Metzler et al., Nature Structural Biol. 1997; 4:527-531.

Affiliated with

Also associated with

Rating

Polypeptides and methods for making the same does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Polypeptides and methods for making the same, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polypeptides and methods for making the same will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4083962