Polypeptides altered to contain an epitope from the Fc region of

Details Polypeptides altered to contain an epitope from the Fc region of Polypeptides altered to contain an epitope from the Fc region of

1995-04-14

2000-08-01

Reeves, Julie

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

53038823, 4241331, 4241451, 435 696, 435 697, 435328, A61K 39395, C07K 1600

Patent

active

060968710

ABSTRACT:
Polypeptides that are cleared from the kidney and do not contain in their original form a Fc region of an IgG are altered so as to comprise a salvage receptor binding epitope of an Fc region of an IgG and thereby have increased circulatory half-life.

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