Polypeptide with type IV collagen cell adhesion, spreading and m

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 15 to 23 amino acid residues in defined sequence

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07K 708, A61K 3700

Patent

active

050829262

ABSTRACT:
A polypeptide having the following formula is provided: gly-val-lys-gly-asp-lys-gly-asn-pro-gly-trp-pro-gly-ala-pro which has the ability to promote cellular adhesion, spreading the motility, while remaining highly cell specific. Medical applications such as chemodiagnostic and chemotherapeutic devices are also provided.

REFERENCES:
patent: 4876332 (1989-10-01), Tsilibary et al.
Glanville et al., Eur. J. Biochem., 152, 213-219, (1985).
Brazel et al., Eur. J. Biochem., 168, 529-536, (1987).
Brinker et al., Proc. Natl. Acad. Sci. U.S.A., vol. 82, pp. 3649-3653, (1985).
Pihlajaniemi et al., J. Biol. Chem., vol. 260, No. 12, pp. 7681-7687, (1985).
R. Timpl et al., Macromolecular Organization of Type IV Collagen, in New in Basement Membrane Research, Raven Press, N.Y., 57-67 (1982).
J. Murray et al., J. Cell Biol., 80, 197-202 (1979).
M. Aumailley et al., J. Cell Biol., 103, 1569-1576 (1986).
T. Herbst et al., J. Cell Biol., 106, 1365-1373 (1988).
M. Kurkinen et al., J. Biol. Chem., 259, 5915-5922 (1984).
S. Sugrue, J. Biol. Chem., 262, 3338-3343 (1987).
K. Tomaselli et al., J. Cell Biol., 105, 2347-2358 (1987).
J. Oberbaumer et al., Eur. J. Biochem., 147, 217-224 (1985).
U. Schwarz-Magdolen et al., Febs. Lett., 208, 203-207 (1986).
D. Brazel et al., Eur. J. Biochem., 172, 35-42 (1988).
R. Soininemi et al., Febs. Lett., 225, 188-194 (1987).
G. Muthukamaran et al., J. Biol. Chem., 264, 6310-6317 (1989).
J. Saus et al., J. Biol. Chem., 264, 6318-6324 (1989).
G. Koliakos et al., J. Biol. Chem., 264, 2313-2323 (1989).
W. Babel et al., Eur. J. Biochem., 143, 545-556 (1984).
E. Tsilibary et al., J. Cell Biol., 103, 2467-2473 (1986).
E. Tsilibary et al., J. Biol. Chem., 263, 19112-19118 (1988); and
M. Chelberg et al., Cancer Research, 49, 4796-4802 (1989).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Polypeptide with type IV collagen cell adhesion, spreading and m does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Polypeptide with type IV collagen cell adhesion, spreading and m, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polypeptide with type IV collagen cell adhesion, spreading and m will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-116414

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.