Chemistry: analytical and immunological testing – Involving production or treatment of antibody
Patent
1985-08-15
1989-02-21
Marantz, Sidney
Chemistry: analytical and immunological testing
Involving production or treatment of antibody
436548, 436804, 436813, 530300, 530324, 530326, 530387, 514 2, 514 12, 514 13, G01N 3353, G01N 33534
Patent
active
048064920
ABSTRACT:
Novel polypeptides, polynucleotide sequences, DNA constructs and compositions are provided for the preparation and use of polypeptides associated with naturally occurring polypeptides found in brains. The small molecular weight polypeptides are growth inhibitors for neoplastic cells without inhibiting normal cells. The polypeptides comprise specific regions which are highly conserved, separated by less conserved regions. The polypeptides find use in inhibiting neoplastic growth and detecting receptors for the polypeptides. Antibodies are provided in conjunction with the polypeptides, which may be used together or separately for detecting the presence of the neoplastic cell retarding polypeptides.
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Marquardt Hans
Shoyab Mohammed
Todaro George J.
Marantz Sidney
Oncogen Inc.
Rae-Venter Barbara
Rowland Bertram I.
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