Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing
Reexamination Certificate
2011-06-21
2011-06-21
Spector, Lorraine (Department: 1649)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
C530S327000
Reexamination Certificate
active
07964554
ABSTRACT:
The present invention discloses anti-histone H1 monoclonal antibodies, hybridomas for the production thereof, and polypeptides, which are useful for suppressing, predicting, or diagnosing transplant rejection in organ transplantation.
REFERENCES:
patent: 6204242 (2001-03-01), Bae et al.
patent: 2004/0052780 (2004-03-01), Ono et al.
patent: 2004-149507 (2004-05-01), None
patent: 99/37318 (1999-07-01), None
patent: 99/45955 (1999-09-01), None
Schett et al., Arthritis and Rheumatism, 47(8):1446-1455, 1998.
Chen et al., J. Gastroenterology and Hepatology, 13:483-489, 1998.
Feng et al., Clinical Chemistry, 50(2):416-422, 2004.
Nakano et al., Transplantation, 77(10):1595-1603, May 2004.
Fournel et al., Current Protein and Peptide Science, 4(4): 261-276, 2003.
Stemmer et al., Molecular Immunology, 31(14):1037-1046, 1994.
Nakano et al., Transpl Immunol, 19(2):87-92, May 1, 2008.
Supplementary European Search Report issued Apr. 14, 2010 in International (PCT) Application No. PCT/JP2005016268.
Gillissen, Guenther, “Immunosuppressive effect of histone in transplantation immunity. Comparative studies with cyclophosphamide”, XP002574784, retrieved from STN Database Accession No. 1970:496837-Abstract. *Zeitschrift Fuer Die Gesamte Experimentelle Medizin, vol. 152, No. 4, 1970, pp. 335-351, ISSN: 0372-8722.
S. Dousson et al., “Histone H1° mapping using monoclonal antibodies”, European Journal of Immunology, vol. 19, No. 6, Jun. 1989, pp. 1123-1129.
T. Nakano et al., “Liver Transplantation-Induced Antihistone H1 Autoantibodies Suppress Mixed Lymphocyte Reaction”, Transplantation, vol. 77, No. 10, May 27, 2004, pp. 1595-1603.
N. Tuaillon et al., “Sequence analysis and fine specificity of two human monoclonal antibodies to histone H1”, Molecular Immunology, vol. 31, No. 4, Mar. 1994, pp. 269-277.
Goto Shigeru
Goto Takeshi
Kawamoto Seiji
Ono Kazuhisa
Sato Shuji
Amateraspharma Inc.
MacFarlane Stacey
Spector Lorraine
Wenderoth , Lind & Ponack, L.L.P.
LandOfFree
Polypeptide that binds anti-histone H1 antibody does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Polypeptide that binds anti-histone H1 antibody, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polypeptide that binds anti-histone H1 antibody will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2709048