Polypeptide of a hybrid surface protein by bacteria

Details Polypeptide of a hybrid surface protein by bacteria Polypeptide of a hybrid surface protein by bacteria

1994-07-26

1997-04-01

Warden, Jill

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

15 to 23 amino acid residues in defined sequence

530327, 530328, 530329, A61K 3800, C07K 500, C07K 700, C07K 1700

Patent

active

056166869

ABSTRACT:
Process is described for the delivery and expression of hybrid surface proteins to the surface of bacteria. The transformed bacteria are useful as vaccines, for the delivery of other active peptides to animal hosts, as diagnostic reagents, and for other purposes.

REFERENCES:
patent: 4705684 (1987-11-01), Beachey
patent: 4784948 (1988-11-01), Scott et al.
Hollingshead et al., The Journal of Biological Chemistry, vol. 261, No. 4, 1986, pp. 1677-1686.
Fischetti et al., J. Exp. Med., vol. 159, 1984. pp. 1083-1095.
Davis et al., Cell, vol. 41, 1985, pp. 607-614.
Scott et al., Proc. Natl. Acad. Sci., vol. 82, 1985, 1822-1826.
Hruby et al., Proc. Natl. Acad. Sci., vol. 85, 1988, pp. 5714-5417.
Nakhasi et al., The Journal of Biological Chemistry, vol. 261, No. 35, 1986, pp. 16616-16621.
Miller et al., The Journal of Biological Chemistry vol. 263, No. 12, 1988, pp. 5668-5673.
Fahnestock et al., Journal of Bacteriology, vol. 167, No. 3, 1986, pp. 870-880
Peptide Hormones, J. A. Parsons, Ed., Jun. 1976, U. Park Press., pp. 1-7--Rudinger.

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