Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is inorganic
Reexamination Certificate
2007-02-06
2007-02-06
Ceperley, Mary E. (Department: 1641)
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
Carrier is inorganic
C436S531000, C436S527000, C435S188000, C530S402000, C530S408000, C530S811000, C530S812000, C530S815000
Reexamination Certificate
active
09923760
ABSTRACT:
A substrate comprises a surface, and a plurality of moieties, on at least a portion of the surface. The moieties are moieties of formula:in-line-formulae description="In-line Formulae" end="lead"?Surf-L—Q—T,in-line-formulae description="In-line Formulae" end="tail"?where —T comprises a reactant ligand, and Surf- designates where the moiety attaches to the surface. The substrate can be made into a protein chip by the reaction of a reactant ligand and a fusion polypeptide, where the fusion polypeptide includes a capture polypeptide moiety which corresponds to the reactant ligand.
REFERENCES:
patent: 4981611 (1991-01-01), Kolattukudy et al.
patent: 5196478 (1993-03-01), Varga et al.
patent: 5223488 (1993-06-01), Ogata et al.
patent: 5232913 (1993-08-01), Ohmori et al.
patent: 5274177 (1993-12-01), Ohmori et al.
patent: 5352594 (1994-10-01), Poulouse
patent: 5389536 (1995-02-01), Gray et al.
patent: 5541162 (1996-07-01), Ohmori et al.
patent: 5545621 (1996-08-01), Kauvar et al.
patent: 5556942 (1996-09-01), Kauvar et al.
patent: 5599903 (1997-02-01), Kauvar et al.
patent: 5616563 (1997-04-01), Creighton et al.
patent: 5646177 (1997-07-01), Koch et al.
patent: 5654176 (1997-08-01), Smith
patent: 5767086 (1998-06-01), Kauvar et al.
patent: 5773236 (1998-06-01), Diwu et al.
patent: 5804604 (1998-09-01), Frankel et al.
patent: 5880097 (1999-03-01), Lyttle et al.
patent: 5908919 (1999-06-01), Kauvar et al.
patent: 5955432 (1999-09-01), Kauvar et al.
patent: 6013462 (2000-01-01), Kauvar et al.
patent: 6030950 (2000-02-01), Ohlenschlager
patent: 6066715 (2000-05-01), Desmarais et al.
patent: 6184344 (2001-02-01), Kent et al.
patent: 6194550 (2001-02-01), Gold et al.
patent: 6207446 (2001-03-01), Szostak et al.
patent: 6214553 (2001-04-01), Szostak et al.
patent: 6537749 (2003-03-01), Kuimelis et al.
patent: 2002/0182597 (2002-12-01), Kuimelis et al.
patent: 0 402 226 (1990-12-01), None
patent: 0 645 397 (1995-03-01), None
patent: WO 91/00357 (1991-01-01), None
patent: WO 95/08563 (1995-03-01), None
patent: WO 95/20601 (1995-08-01), None
patent: WO 96/22791 (1996-08-01), None
patent: WO 98/14476 (1998-04-01), None
patent: WO 98/16508 (1998-04-01), None
patent: WO 98/30575 (1998-07-01), None
patent: WO 98/30578 (1998-07-01), None
patent: WO 98/47910 (1998-10-01), None
patent: WO 99/34839 (1999-07-01), None
patent: WO 99/51773 (1999-10-01), None
patent: 01/04265 (2001-01-01), None
Alam, J., et al. “Reporter genes: Application to the study of mammalian gene transcription,”Analytical Biochemistry, vol. 188, 1990, pp. 245-254.
Alligood, K., et al., “The Formation of a Covalent Complex Between a Dipeptide Ligand and the src SH2 Domain,”Bioorg Med ChemLett. vol. 8, 1998, pp. 1189-1194.
Austin, C.,et al., “Cellular Migration Patterns in the Developing Mouse Cerebral Cortex,”Development, vol. 110, 1990, pp. 713-732.
Bamdad, C., “A DNA Self-Assembled Monolayer for the Specific Attachment of Unmodified Double- or Single-Stranded DNA,”Biophys Journal, vol. 75, 1998, pp. 1997-2003.
Bandmann, N., et al., “Genetic Engineering of the Fusarium Solani Pisi Lipase Cutinase for Enhanced Partitioning in PEG-phosphate Aqueous Two-phase Systems,”Journal of Biotechnology, vol. 79, 2000, pp. 161-172.
Bechtold, N., and G. Pelletier. 1998. In planta Agrobacterium-mediated transformation of adultArabidopsis thalianaplants by vacuum infiltration,Methods Mol Biol., 82:259-266.
Becker, D.M., et al., “High-efficiency Transformation of Yeast by Electroporation,”Methods Enzymology, vol. 194, 1991, pp. 182-187.
Beggs, J.D. “Transformation of Yeast by a Replicating Hybrid Plasmid,”Nature, vol. 275, 1978, pp. 104-109.
Berger, J., et al., “Secreted Placental Alkaline Phosphatase: A Powerful New Qunatitative Indicator of Gene Expression in Eukaryotic Cells,”Gene, vol. 66, 1988, pp. 1-10.
Berggren, K., et al., “Partitioning of Peptides and Recombinant Protein-Peptide Fusions in Thermoseparating Aqueous Two-phase Systems: Effect of Peptide Primary Structure,”Journal of Chromatogr B Biomed Sci Appl., vol. 743, 2000, pp. 295-306.
Berman, H.A., et al., “Fluorescent Phosphonate Label for Serine Hydrolases, Pyrenebutyl Methylphosphonofluoridate: Reaction with Acetylcholinesterase.”Biochemistry, vol. 17, 1978, pp. 1704-1713.
Blaydes, J.Petal., “The Development and use of Phospho-Specific Antibodies to Study Protein Phosphorylation,”Methods Mol Biol.vol. 99, 2000, pp. 177-189.
Bodine, D.M., et al., “Survival and Retrovirus Infection of Murine Hematopoietic Stem Cells In Vitro: Effects of 5-FU and Method of Infection,”Experimental Hematology, vol. 19, 1991, pp. 206-212.
Born, Timothy et al., “4-(Fluoromethyl)phenyt Phasphate Acts As a Mechanism-Based Inhibitor of Calcineurin”,Jorn. Bio. Chem., vol. 270, No. 43, 1995, pp. 25651-25655.
Brown, M.T., et al., “Regulation, Substrates and Functions of src,”Biochim Biophys Acta., vol. 1287, 1996, pp. 121-149.
Capecchi, M.R. “High Efficiency Transformation by Direct Microinjection of DNA Into Cultured Mammalian Cells,”Cell, vol. 22, 1980, pp. 479.
Case, M.E., et al., “Efficient Transformation of Neurospora Crassa by Utilizing Hybrid Plasmid DNA,”Proceedings of the National Academy of Sciences of the United States of America, vol. 76, Oct. 1996, pp. 5259-5263.
Cepko, C.L., et al., “Construction and Applications of a Highly Transmissible Murine Retrovirus Shuttle Vector,”Cell, vol. 37, Jul. 1984, pp. 1053-1062.
Chalfie, M., et al., “Green Fluorescent Protein as a Marker for Gene Expression,”Science, vol. 263, Feb. 11, 1994, pp. 802-805.
Chaney, W.G., et al., “High-frequency Transfection of CHO Cells Using Polybrene,”SomaticCell and Molecular Genetics, vol. 12, Jan. 1986, pp. 237-244.
Chapman, R., et al., “Surveying for Surfaces That Resist the Adsorption of Proteins,” Journalof American Chem. Society, vol. 122, 2000, pp. 8303-8304.
Chen, C., et al., “Calcium Phosphate-Mediated Gene Transfer: A Highly Efficient Transfection System for Stably Transforming Cells with Plasmid DNA,”BioTechniques, vol. 6, No. 7, 1988, pp. 632-638.
Chen, C.S., et al., “Geometric Control of Cell Life and Death.”Science, vol. 276, 1997, pp. 1425-1428.
Chmura, Albert et al., “Antibodies with Infinite Affinity”,PNAS, vol. 98, No. 15, 2001, pp. 8480-8484.
Cohen, S.N., et al., “Nonchromosomal Antibiotic Resistance in Bacteria: Genetic Transformation ofEscherichia coliby R-Factor DNA,”Proceedings of the National Academy of Sciences of the United States of America, vol. 69, No. 8, Aug. 1972, pp. 2110-2114.
de Louvencourt, L., et al., “Transformation ofKluyveromyces lactisby Killer Plasmid DNA,”Journal of Bacteriology, vol. 154, No. 2, May 1983, pp. 737-742.
Deussen, H.J., et al., “Design and Synthesis of Triglyceride Analogue Biotinylated Suicide Inhibitors for Directed Molecular Evolution of Lipolytic Enzymes,”Bioorg Med Chem Lett., vol. 10, 2000, pp. 2027-2031.
Deussen, H.J., et al., “A Novel Biotinylated Suicide Inhibitor for Directed Molecular Evolution of lipolytic Enzymes,”Bioorg Med Chem., vol. 8, 2000, pp. 507-513.
de Wet, J.R., et al., “Firefly Luciferase Gene: Structure and Expression in Mammalian Cells,”Molecular Cellular Biology, vol. 7, Feb. 1987, pp. 725-737.
Elroy-Stein, O., et al., “Cytoplasmic Expression System Based on Constitutive Synthesis of Bacteriophage T7 RNA Polymerase in Mammalian Cells,”Proceedings of the National Academy of Sciences of the United States of America, vol. 87, No. 17, Sep. 1990, pp. 6743-6747.
Escudero, J., et al., “Transfer and Integration of T-DNA without Cell Injury in the Host Plant,”Plant Cell, vol. 9, Dec. 1997, pp. 2135-2142.
Fekete, D.M., et al., “Retroviral Infection Coupled with Tissue Transplantation Limits Gene Transfer in the Chicken
Hodneland Christian
Mrksich Milan
Brinks Hofer Gilson & Lione
Ceperley Mary E.
The University of Chicago
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