Polypeptide having gamma-interferon activity lacking amino acids

Details Polypeptide having gamma-interferon activity lacking amino acids Polypeptide having gamma-interferon activity lacking amino acids

1987-09-30

1990-05-01

Hazel, Blondel

Drug, bio-affecting and body treating compositions

Lymphokine

Interferon

530351, 435811, A61K 4502, C07K 1526, C12P 2100

Patent

active

049216988

ABSTRACT:
A polypeptide having gamma-interferon activity which lacks the amino acid sequence coded for by exon 4, a polynucleotide sequence which codes for said polypeptide, a replicable expression vehicle containing said polynucleotide sequence and a transformed microorganism containing said replicable expression vehicle are disclosed. The transformed microorganism is useful for preparing the polypeptide having gamma-interferon activity.

REFERENCES:
patent: 4604284 (1986-08-01), Kang et al.
Gray et al., Nature, vol. 295, pp. 503-508, 1982.
Davis et al., Nucleic Acid Research, vol. 10, pp. 2487-2500, 1982.
Yujiro Higashi et al., "The Third Annual International Congress for Interferon Research", Miami, Fla., Nov. 1-3, 1982.
Capon et al., "The Third Annual International Congress for Interferon Research", Miami, Fla., Nov. 1-3, 1982.

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