Polypeptide factors from colostrum

Details Polypeptide factors from colostrum Polypeptide factors from colostrum

1986-01-17

1989-09-12

Moskowitz, Margaret

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 2, 514 21, 530350, 530387, 530395, 530832, 530351, A61K 3702, C07K 1506

Patent

active

048660370

ABSTRACT:
IgE binding factors (IgE-bfs) with IgE suppressor (IgE-SF) activity obtainable from human colostrum in an enriched form, a method for the prevention and/or the treatment of allergy by administering the IgE-bfs and pharmaceutical compositions comprising said IgE-bfs.

REFERENCES:
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Zuran et al., J. Immunol., 127(3), 1169-77, (1981).
PCT WO 81/00813 published 4/2/81.
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Katz, D. H. et al., Regulation of the IgE Antibody System in Humans and Experimental Animals, Progress in Immunology, 5th ed., Y. Yamamura & T. Toda, Acad. Press, (1983), p. 465.
Sarfati, M. et al., In Vitro Synthesis of IgE by Binding Factors Secreted by RPMI 8866 Lymphoblastoid B cells of Human Lymphocytes, II. Immunology, (1984), 53:197.
Huff, T. F. et al., Formation of IgE-Binding Factors by Human T Cell-Hybridomas. Proc. Natl. Acad. Sci., (U.S.A.), (1984), 81:1514.
Sandberg, K. et al., IgE-Binding Factors in Atopic Eczema, (1983), in Proceed. of XI Int. Congress Allergy Clin. Immunol., MacMillan p. 105.
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Mohr, J. A., The Possible Induction and/or Acquistion of Cellular Hypersensitivity Associated with Ingestion of Colostrum., J. Pediat., (1973), 82:1002.
Cruz, J. R. et al., Food Antibodies in Milk from Guatemalan Women, J. Pediat., (1981), 93:600.
Frick, O. L. et al., Development of Allergy in Children, J. Allergy Clin. Immunol., (1979), 63:228.
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Kjellman, N.-I. M. et al., Cord Blood IgE Determination for Allergy Predication. Annals of Allergy, (1984), 53:167.
Jarret, E. E. E. et al., Selective Suppression of IgE Antibody Responsiveness by Material Influence. Nature, (Lond), (1973), 280:45.
Roberts, S. A. et al., Specific Suppression of Rat IgE Responses with Milk from Immunized Females and with Feed of Serum Antibody Immunology, (1983), 48:195.
Richie, E. R. et al., Distribution of T Lymphocytes Subsets in Human Colostrum. J. Immunol., (1982), 129:1116.
Parmely, M. J. et al., In Vitro Studies on the T-Lymphocyte Populations of Human Milk. J. Exp. Med., (1976), 144:358.

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