Polypeptide compositions formed using a coiled-coil template...

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Synthesis of peptides

Reexamination Certificate

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Details

C530S300000, C530S324000, C530S387300, C530S388200, C424S184100, C424S185100

Reexamination Certificate

active

11059582

ABSTRACT:
The invention relates to the use of constrained coiled-coil polypeptides to mimic α-helical structural elements of native proteins. These constrained peptidyl mimetics are used to generate and/or identify ligands which selectively bind the α-helical segment contained in the native protein.

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