Polypeptide compositions formed using a coiled-coil template...

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Synthesis of peptides

Reexamination Certificate

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Details

C300S013000, C300S013000, C300S013000, C424S184100, C424S185100, C435S007100, C435S069700

Reexamination Certificate

active

06872806

ABSTRACT:
The invention relates to the use of constrained coiled-coil polypeptides to mimic α-helical structural elements of native proteins. These constrained peptidyl mimetics are used to generate and/or identify ligands, which selectively bind the α-helical segment contained in the native protein.

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patent: WO 9315110 (1993-08-01), None
patent: WO 9531480 (1995-11-01), None
Prusiner et al. Jun. 3, 1997, Database: Issued_Patents_AA, Accession No.: US-08-868-162A-21, Seq ID No.: 5 alignment result 6.*
Prusiner et al. Jun. 3, 1997, Database: Issued_Patents_AA, Accession No.: US-08-868-162A-21, Seq ID No.: 7 alignment result 6.*
Fishleigh et al. Jun. 2, 1994, Database: Issued_Patents_AA, Accession No.: US-08-244-701B-36, Seq ID No.: 6 alignment result 1.

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