Polypeptide bombesin antagonists

Details Polypeptide bombesin antagonists Polypeptide bombesin antagonists

1993-03-15

1994-11-29

Lee, Lester L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 14, 514 16, 530300, 530328, 530327, A61K 3700, A61K 3702, C07K 500, C07K 700

Patent

active

053690940

ABSTRACT:
Pseudopeptides comprising a peptide of formula I:

REFERENCES:
patent: 5068222 (1991-11-01), Camble et al.
patent: 5081107 (1992-01-01), Cotton et al.
patent: 5084555 (1992-01-01), Coy et al.
patent: 5100873 (1992-03-01), de Castiglione et al.
patent: 5162497 (1992-11-01), Coy et al.
patent: 5217955 (1993-06-01), Bogden et al.
"Pseudononapeptide Bombesin Antagonists Containing C-Termina Trp or Tpi" Cai, et al. pp. 267-271, Peptides vol. 13, 1992.
"Inhibition of Growth of UT-29 Human Colon Cancer Xenografts in Nude Mice by Treatment with Bombesin/Gastrin Releasing Peptide Antagonist (RC-3095).sup.1 ", Cancer Research 51, 6006-6009, 1991.
Cai et al., Peptides, vol. 13, pp. 267-271, 1992.

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