Polyol/oil suspensions for the sustained release of proteins

Details Polyol/oil suspensions for the sustained release of proteins Polyol/oil suspensions for the sustained release of proteins

2005-12-27

2005-12-27

Chernyshev, Olga N. (Department: 1646)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C514S964000, C514S965000, C530S350000, C530S399000, C424S085400

Reexamination Certificate

active

06979674

ABSTRACT:
The present invention relates to the preparation of polyol/thickened oil suspensions containing a biologically active agent, for the sustained delivery of the biologically active agent. The described protein/glycerol/oil suspensions show sustained release of protein, e.g., G-CSF, of up to at least one week.

REFERENCES:
patent: 2491537 (1949-12-01), Welch
patent: 2507193 (1950-05-01), Buckwalter
patent: 2964448 (1960-12-01), Anschel
patent: 4371523 (1983-02-01), Grodsky et al.
patent: 4439181 (1984-03-01), Blackshear et al.
patent: 4675189 (1987-06-01), Kent et al.
patent: 4695463 (1987-09-01), Yang et al.
patent: 4695623 (1987-09-01), Stabinsky
patent: 4703008 (1987-10-01), Lin
patent: 4810643 (1989-03-01), Souza
patent: 4855134 (1989-08-01), Yamahira et al.
patent: 4897471 (1990-01-01), Stabinsky
patent: 4977140 (1990-12-01), Ferguson et al.
patent: 4999291 (1991-03-01), Souza
patent: 5075222 (1991-12-01), Hannum et al.
patent: 5372808 (1994-12-01), Blatt et al.
patent: 5411951 (1995-05-01), Mitchell
patent: 5441868 (1995-08-01), Lin
patent: 5541293 (1996-07-01), Stabinsky
patent: 5547933 (1996-08-01), Lin
patent: 5581476 (1996-12-01), Osslund
patent: 5582823 (1996-12-01), Souza
patent: 5618698 (1997-04-01), Lin
patent: 5621080 (1997-04-01), Lin
patent: 5789198 (1998-08-01), Akerblom
patent: A 76380/91 (1991-11-01), None
patent: A 10948/92 (1992-08-01), None
patent: 0 243 153 (1987-10-01), None
patent: 0 272 703 (1988-06-01), None
patent: 0 335 423 (1989-04-01), None
patent: 0 374 120 (1990-06-01), None
patent: 0 459 630 (1991-12-01), None
patent: 0 473 268 (1992-03-01), None
patent: WO 85/02118 (1985-05-01), None
patent: WO 89/10932 (1989-11-01), None
patent: WO 91/05795 (1991-05-01), None
patent: WO 91/05798 (1991-05-01), None
patent: WO 92/17505 (1992-10-01), None
patent: WO 94/00913 (1994-01-01), None
patent: WO 94/09257 (1994-04-01), None
patent: WO 94/17185 (1994-08-01), None
patent: WO 95/17206 (1995-06-01), None
patent: WO 96/05309 (1996-02-01), None
patent: WO 96/18417 (1996-06-01), None
patent: WO 96/40912 (1996-12-01), None
patent: WO 97/00128 (1997-01-01), None
patent: WO 97/01331 (1997-01-01), None
patent: WO 97/06816 (1997-02-01), None
patent: WO 97/23614 (1997-07-01), None
patent: WO 97/01010 (1997-09-01), None
Sims et al., J. American Oil Chemists' Soc., 1977, 54, No. 1, pp. 4-7.
Wise, et al., “Polylactic Acid as a Biodegradable Carrier for Contraceptive Steroids”,Contraception, vol. 8(3), pp. 227-234, (1973).
Hutchinson, et al., “Biodegradable Polymers for the Sustained Release of Peptides”,Biochemistry Social Trans., vol. 13, pp. 520-523, (1985).
Creighton, et al.,Proteins, passim(W.H. Freeman and Company, N.Y. 1984).
Ford, et al., “Fusion Tails for the Recovery and Purification of Recombinant Proteins”,Protein Expression and Purification, vol. 2, pp. 95-107, (1991).
Lu, et al., “Folding and Oxidation of Recombinant Human Granulocyte Colony Stimulating Factor Produced inEscherichia coli”, The Journal of Biological Chemistry, vol. 267 (13), pp. 8870-8777, (1992).

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