Polyol esters, their preparation and use in depot forms of pharm

Details Polyol esters, their preparation and use in depot forms of pharm Polyol esters, their preparation and use in depot forms of pharm

1992-02-11

1999-07-13

Peselev, Elli

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

424 78, 536119, A61K 3170

Patent

active

059226820

ABSTRACT:
This invention provides a polyester of a polyol, said polyol containing at least 3 hydroxyl groups and having a molecular weight of up to 20,000 at least 1 hydroxyl group in said polyol being in the form of an ester, with a poly- or co-poly-lactic acid residue, each having a molecular weight of at least 5,000. These are useful for parenteral depot formulations.

REFERENCES:
patent: 3773919 (1973-11-01), Boswell et al.
patent: 3887699 (1975-06-01), Yolles
patent: 3963699 (1976-06-01), Rizzi et al.
patent: 4165432 (1979-08-01), Preston et al.
patent: 4334061 (1982-06-01), Bossier, III
patent: 4451452 (1984-05-01), Deibig et al.
patent: 4452973 (1984-06-01), Casey et al.
patent: 4526938 (1985-07-01), Churchill et al.
Schindler, et al. Journal of Polymer Science: Polymer Chemistry Ed., vol. 20, pp. 319-326 (1982).

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