Polynucleotides which code for cyanide-tolerant nitrile...

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase

Reexamination Certificate

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C435S129000, C435S183000, C435S252300, C536S023200

Reexamination Certificate

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07943359

ABSTRACT:
Disclosed herein are cyanide-tolerant nitrile hydratases especially fromPseudomonas putidaorPseudomonas marginalisstrains which exhibit increased cyanide tolerance. Also disclosed are methods of preparing amides from nitriles in the presence of cyanides and polynucleotide sequences coding for cyanide-tolerant nitrile hydratases.

REFERENCES:
Chica et al. Curr Opin Biotechnol. Aug. 2005;16(4):378-84.
Sen et al. Appl Biochem Biotechnol. Dec. 2007;143(3):212-23.
Accession AAQ13362. Nov. 13, 1991.
Beppu et al. Accession AAR13831, Nov. 13, 1991.
International Search Report and Written Opinion mailed Nov. 9, 2006 in PCT/EP2005-002689.

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