Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2004-05-26
2009-11-03
Stucker, Jeffrey (Department: 1649)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S320100, C435S325000, C536S023100, C536S023500
Reexamination Certificate
active
07611865
ABSTRACT:
Disclosed are novel proteins, referred to as truncated glial cell line-derived neurotrophic factor (truncated GDNF) proteins, that promote dopamine uptake by dopaminergic cells and promote the survival of nerve cells. Also disclosed are processes for obtaining the truncated GDNF proteins by recombinant genetic engineering techniques.
REFERENCES:
patent: 4419446 (1983-12-01), Howley et al.
patent: 4518584 (1985-05-01), Mark et al.
patent: 4892538 (1990-01-01), Aebischer et al.
patent: 5011472 (1991-04-01), Aebischer et al.
patent: 5106627 (1992-04-01), Aebischer et al.
patent: 5202428 (1993-04-01), Schubert
patent: 5252714 (1993-10-01), Harris et al.
patent: 5272071 (1993-12-01), Chappel
patent: 5733875 (1998-03-01), Martin
patent: 5741778 (1998-04-01), Martin et al.
patent: 6184200 (2001-02-01), Hu
patent: 6245330 (2001-06-01), Horellou et al.
patent: 7390781 (2008-06-01), Hu
patent: 2004/0214776 (2004-10-01), Hu
patent: 154 316 (1985-03-01), None
patent: 401 384 (1989-12-01), None
patent: 398 753 (1990-05-01), None
patent: 423 980 (1990-10-01), None
patent: WO 91/03568 (1991-03-01), None
patent: WO 91/10425 (1991-07-01), None
patent: WO 91/10470 (1991-07-01), None
patent: WO 93/06116 (1993-04-01), None
patent: WO 95/17203 (1995-06-01), None
patent: WO 95/26408 (1995-10-01), None
patent: WO 97/08196 (1997-03-01), None
Varon et al., (1978)Ann. Rev. Neuroscience1:327-361.
Thoenen et al., (1985)Science229:238-242.
Rich et al., (1987)J. Neurocytol. 15:261-268.
Otto et al., (1987)Neurosci. Lett. 83:156-160.
Hamburger et al., (1984)J. Neurosci. 4:767-774.
Apfel et al., (1991)Ann. Neurol. 29:87-90.
Hofer et al., (1988)Nature331:261-262.
Lin et al., (1989)Science246:1023-1025.
Fausset et al., (1991)Electrophoresis12:22-27.
Dayhoff, (1972)Atlas of Protein Sequence and Structure5:124.
Cunningham et al., (1989)Science244:1081-1085.
Francis, (1992)Focus on Growth Factors3(2):4-10.
Malik et al., (1992)Exp. Hematol. 20:1028-1035.
Chamow et al., (1994)Bioconjugate Chem. 5:133-140.
Maniatis et al., (1982)Molecular Cloning(A Laboratory Manual), 387-389.
Engels et al., (1989)Chem. Intl. Ed., 28:716-734.
Wells et al., (1985)Gene34:315-323.
Urlaub et al., (1980)Proc. Natl. Acad. Sci., USA 77(7):4216-4220.
Takebe et al., (1988)Mol. Cell. Biol. 8(1):466-472.
Sambrook, (1981)Nature293:620-625.
Kaufman et al., (1985)Mol. Cell. Biol. 5(7):1750-1759.
Kucherlapati, (1989)Prog. in Nucl. Acid Res. and Mol. Biol. 36:301-310.
Thomas et al., (1986)Cell44:419-428.
Thomas et al., (1987)Cell51:503-512
Doetschman et al., (1988)Proc. Natl. Acad. Sci. 85:8583-8587.
Doetschman et al., (1987)Nature330:576-578.
Winn et al., (1991)Exper. Neurol. 113:322-329.
Aebischer et al., (1991)Exper. Neurol. 111:269-275.
Tresco et al., (1992)ASAIO38:17-23.
Okayama et al., (1983)Mol. Cell . Biol. 3:280-289.
Goodwin et al. (1983)Nucleic Acids Res. 11:6873-6882.
Gasser et al. (1982)Proc. Natl. Acad. Sci. 79:6522-6526.
Erlich, Ed., (1989)PCR Technology, Principles and Applications for DNA Amplification, Chapter 6:61-70.
Louis et al., (1992)J. Pharmacol. Exp. Therap. 262:1274-1283.
Louis et al., (1993)Science259:689-692.
Lin et al., (1994)J. Neurochem. 63(2): 758-768.
Friedman et al., (1987)Neuro. Sci. Lett. 79:65-72.
Schubert et al., (1974)Nature249:224-227.
Lin et al., (1993)Science260:1130-1132.
Bohn et al., (1989)Soc. Neurosci. Abs. 15:277.
Schaar, et al. (1994), “Multiple Astrocyte Transcripts Encode Nigral Trophic Factors in Rat and Human”Exp. Neurology130:387-393.
Bohn, Martha C., et al., “Dopaminergic Neurons Protected from Degeneration by GDNF Gene Therapy,” Science, vol. 274, pp. 838-841, Feb. 7, 1997.
Barnett, M. W. et al., “Signalling by glial cell line-derived neurotrophic factor (GDNF) requires heparan sulphate glycosaminoglycan,” J. of Cell Sci., 115:4495-4503, (2002).
Fry, E. J. “Central Nervous System Regeration: Mission Impossible?,” Clinical and Experimental Pharmacology and Physiology 28:253-258, (2001).
Jackowski, A., “Neural injury repair: hope for the future as barriers to effective CNS regeneration become clearer,” British Journal of Neruosurgery, 9:303-317, (1995).
Rickard, S. M., “The binding of human glial cell line-derived neurotrophic factor to heparin and heparan sulfate . . . ,” Glycobiology, vol. 13(6):419-426, (2003).
Sariola, H., “Novel functions and signalling pathways for GDNF,” J. of Cell Sci., 116:3855-3862, (2003).
Zang, et al.“The Biological Activity of N-Terminally Truncated Forms of GDNF on Cultured Mesencephalic Dopaminergic Neurons,” Soc. For Neuroscience, vol. 22(3):1955, (1996).
Hankins, et al., “Early abnormalities of retinal dopamine pathways in rats with heriditary retinal dystrophy,” Documenta ophthalmologica, 1994, 86:325-334.
Matsuoka, et al., “Experimental Vestibular Pharmacology: a Minireview with Special Reference to Neuroactive Substances . . . ,” Acta Otolaryngol (Stockh), 1985, Suppl. 419:62-70.
Orkin, et al., “Report and Recommendations of the Panel to Assess the NIH Investment in Research on Gene Therapy,” NIH, 1995, pp. 1-41.
Rudinger, “Characteristics of the amino acids as components of a peptide hormone sequence,” in Peptide Hormones, JA Parsons, ed.,University Park Press, Baltimore, 1976, pp 1-7.
Amgen Inc.
Bugaisky Lawrence B.
Gucker Stephen
Stucker Jeffrey
LandOfFree
Polynucleotides encoding truncated glial cell line-derived... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Polynucleotides encoding truncated glial cell line-derived..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polynucleotides encoding truncated glial cell line-derived... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4057347