Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1997-11-03
2000-10-03
Priebe, Scott D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
435 691, 4353201, 435325, 4352523, 43525411, 536 231, 536 232, 536 234, 536 237, A61K 4800, C07H 2100, C12N 1553, C12N 1562, C12N 1563
Patent
active
061273457
ABSTRACT:
The invention provides Glucose 6-Phosphate Dehydrogenase gene polypeptides and DNA (RNA) encoding Glucose 6-Phosphate Dehydrogenase gene polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Glucose 6-Phosphate Dehydrogenase gene polypeptide for the protection against infection, particularly bacterial infections.
REFERENCES:
patent: 5137821 (1992-08-01), Sagai et al.
van den Broek et al. "Isolation and characterization of the glucose-6-phosphate dehydrogenase gene (gsdA) from Aspergiilus niger", Mol. Gen. Genet. 247: 229-239, 1995.
Ngo et al., "Computational complexity, protein structure prediction, and the Levinthal paradox", in The Protein Folding Problem and Tertiary Structure Prediction, Merz et al. (eds.), Birkhauser Boston: Boston, MA, pp. 433 and 492-495, 1994.
Rudinger, "Characteristics of the amino acid as componants of a peptide hormone sequence", in Peptide Hormones, Parsons (ed.), University Park Press: Baltimore, MD, pp. 1-7, Jun. 1976.
Ben-Yedidia et al., "Design of peptide and polypeptide vaccines", Curr. Opin. Biotechnol. 8: 442-448, 1997.
Kobayashi, et al.., GenBank Submission, Accession No. P54547, Glucose-6-phosphate 1-hydrogenase (EC 1.1.1.49)(G6PD), Oct. 1, 1996.
Carter, et al., "Sequence of the Escherichia coli K-12 edd and eda genes of the Entner-Doudoroff pathway." Gene, vol. 130, pp. 155-156, (1993).
Deibert Thomas S.
Gimmi Edward R.
King William T.
Priebe Scott D.
SmithKline Beecham Corporation
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