Polynucleotides encoding stem cell growth factor-like...

Details Polynucleotides encoding stem cell growth factor-like... Polynucleotides encoding stem cell growth factor-like...

2008-01-08

2008-01-08

Qian, Celine (Department: 1636)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S023400, C536S023100, C435S320100, C435S325000, C435S252300, C435S254110

Reexamination Certificate

active

07317099

ABSTRACT:
The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted stem cell growth factor-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA libraries prepared from human fetal liver spleen, ovary, adult brain, lung tumor, spinal cord, cervix, ovary, endothelial cells, umbilical cord, lymphocyte, lung fibroblast, fetal brain, and testis. Other aspects of the invention include vectors containing processes for producing novel human secreted stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides.

REFERENCES:
patent: 4341761 (1982-07-01), Ganfield et al.
patent: 4399121 (1983-08-01), Albarella et al.
patent: 4427783 (1984-01-01), Newman et al.
patent: 4444887 (1984-04-01), Hoffmann
patent: 4451570 (1984-05-01), Royston et al.
patent: 4466917 (1984-08-01), Nussenzweig et al.
patent: 4472506 (1984-09-01), Liburdy
patent: 4491632 (1985-01-01), Wands et al.
patent: 4493890 (1985-01-01), Morris
patent: 2003/0017157 (2003-01-01), St. Croix et al.
patent: WO 00/77037 (2000-12-01), None
Mio et al. Isolation and characterization of a cDNA for human mouse, and rat full-length stem growth factor, a new member of C-type lectin superfamily. Biochem Biophys Res Commun. vol. 249, No. 1, pp. 124-130, Aug. 10, 1998.
Nielsen et al. A neural network method for identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Int J Neural Syst. vol. 8, No. 5-6, pp. 581-599, Oct. -Dec. 1997.
Carson-Walter et al. Cell surface tumor endothelial markers are conserved in mice and humans. Cancer Res. vol. 61, No. 18, pp. 6649-6655, Sep. 15, 2001.
Verma et al. Gene therapy—promises, problems and prospects. Nature. vol. 389, No. 6648, pp. 239-242, Sep. 1997.
Palu et al. In pursuit of new developments for gene therapy of human diseases. J Biotechnol. vol. 68, No. 1, pp. 1-13, Feb. 1999.
Luo et al. Synthetic DNA delivery systems. Nat Biotechnol. vol. 18, No. 1, pp. 33-37, Jan. 2000.
Edelstein et al. Gene therapy clinical trials worldwide 1989-2004-an overview. J Gene Med. vol. 6, No. 6. pp. 597-602, Jun. 2004.
Sigmund et al. Viewpoint: Are studies in genetically altered mice out of control? Arteriocsler Thromb Vasc Biol. vol. 20, No. 6, pp. 1425-1429, 2000.
Wall. Transgenic livestock: Progress and prospects for the future. Theriogenology. vol. 45, pp. 57-68, 1996.
Lehninger et al. Principles of Biochemistry. New York: Worth Publishers, 1993, pp. 200-201.
Altschul et al., “Basic Local Alignment Search Tool,” J. Mol. Biol., 21:403-410 (1990)
Altschul et al., “A Protein Alignment Scoring System Sensitive at All Evolutionary Distances,” J. Mol. Evol. 36:290-300 (1993).
Bjornson et al., “Turning Brain Into Blood: A Hematopoietic Fate Adopted by Adult Neural Stem Cells in Vivo,” Science, 283:534-537 (1999).
Cole et al., “The EBV-Hybridoma Technique and its Application to Human Lung Cancer” inMonoclonal Antibodies and Cancer Therapy, Alan R. Liss, Inc., pp. 77-96 (1985).
Database EST. No. AA166917, ‘WashU-NCI human EST project’, Hillier et al., Nov. 9, 1997.
Database EST. No. AA167076, ‘WashU-NCI human EST project’, Hillier et al., Nov. 9, 1997.
Database EST, No. AA455078, ‘WashU-Merck EST Project 1997’, Hillier et al., Jun. 6, 1997.
Database EST, No. AA715165, National Cancer Institute, Cancer Genome Anatomy Project , NCI-CGAP, Dec. 29, 1997.
Database EST, No. AI206035, ‘National Cancer Institute, Cancer Genome Anatomy Project’, NCI-CGAP, Nov. 29, 1998.
Database EST, No. AI267121, ‘National Cancer Institute, Cancer Genome Anatomy Project’, NCI-CGAP, Jan. 28, 1999.
Database EST, No. AI858126, ‘National Cancer Institute, Cancer Genome Anatomy Project’, NCI-CGAP, Mar. 7, 2000.
Database EST, No. AW195729, ‘National Cancer Institute, Cancer Genome Anatomay Project’, NCI-CGAP, Nov. 29, 1999.
Database EST, No. BE536256, ‘National Institutes of Health, Mammalian Gene Collection’, NIH-MGC, Aug. 9, 2000.
Database EST, No. BE751745, ‘Design and use of four pooled tissue normalized cDNA libraries for EST discovery in cattle’, Smith et al., Sep. 15, 2000.
Database EST, No. W78038, The WashU-Merck EST Project, Hillier et al., Oct. 17, 1996.
Database GenEmbl, No. AL353790, ‘Direct submission’, SIMS, Aug. 10, 2000.
Database GenEmbl, No.I AC068709, ‘Genome Therapeutics Corporation Sequencing Center: Human Genome Sequence Data’, Smith, May 7, 2000.
Dias Neto et al. “Shotgun Sequencing of the Human Transcriptote with ORF Epressed Sequence Tags.” Proc. Natl. Acad. Sci. USA, 97:3491-3496 (2000).
Hiraoka et al., “Monoclonal Antibodies Against Human Hematopoietic Survival and Growth Factor,” Biomed. Biochim. ACTA, 46:419-427 (1987).
Hiraoka et al., “Production of Human Hematopoietic Survival and Growth Factor by a Myeloid Leukemia Cell Line (KPB-M15) and Placenta as Detected by a Monoclonal Antibody,” Cancer Reserch, 47:5025-5030 (1987).
Kozbor et al., “The Production of Monoclonal Antibodies From Human Lymphocytes,” Immunol. Today, 4:72-79 (1983).
Kyte and Doolittle, “A Simple Method for Displaying the Hydropathic Character of a Protein,” J. Mol. Biol., 157:105-132 (1982).
Pearson, “Rapid and Sensitive Sequence Comparison with FASTP and FASTA,” Methods in Enzymology, 183:63-98 (1990).
Osawa et al., “Long-Term Lymphohematopoietic Reconstitution by a Single CD34-Low/Negative Hematopoietic Stem Cell,” Science, 273:242-245 (1996).
St. Croix et al., “Genes Expressed in Human Tumor Endothelium,” Science, 289:1197-1201 (2000).
Thompson et al., “Embryonic Stem Cell Lines Derived from Human Blastocysts,” Science, 282:1145-1147 (1998).
Wang et al. Large-Scale Identification, Mapping, and Genotyping of Single-Nucleotide Polymorphisms in the Human Genome, Science, 280:1077-1082 (1998).
Watt and Hogan, “Out of Eden: Stem Cells and Their Niches,” Science, 287:1427-1430 (2000).
International Search Report, PCT/US00/35260, United States Searching Authority.

Affiliated with

Also associated with

Rating

Polynucleotides encoding stem cell growth factor-like... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Polynucleotides encoding stem cell growth factor-like..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polynucleotides encoding stem cell growth factor-like... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2772781