Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2007-04-25
2011-12-06
Wang, Chang-Yu (Department: 1649)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C435S069100, C435S070100, C435S070300, C435S071100, C435S320100, C435S455000
Reexamination Certificate
active
08071745
ABSTRACT:
Disclosed are methods and compositions for early diagnosis, monitoring and treatment of retinal dystrophy, age-related macular degeneration, Bardet-Biedel syndrome, Bassen-kornzweig syndrome, best disease, choroidema, gyrate atrophy, congenital amourosis, refsun syndrome, stargardt disease and Usher syndrome. In particular, the invention relates to a protein, termed “Rdcvf1,” that is differentially transcribed and expressed in subjects suffering from retinal dystrophies and the like, such as retinal dystrophy and age-related macular degeneration compared with non-sufferers, antibodies which recognize this protein, and methods for diagnosing such conditions.
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Hicks David
Léveillard Thierry
Mohand-Said Saddek
Sahel José Alain
DiGiorgio, Esq. Jeanne M.
Nelson Mullins Riley & Scarborough LLP
Novartis AG
Sloper, Esq. Jill Gorny
Universite de Strasbourg
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