Polynucleotides encoding members of the human B lymphocyte...

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Reexamination Certificate

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C514S021200

Reexamination Certificate

active

07968680

ABSTRACT:
The present invention provides novel isolated BLAA polynucleotides and the membrane-associated or secreted polypeptides encoded by the BLAA polynucleotides. Also provided are the antibodies that immunospecifically bind to a BLAA polypeptide or any derivative, variant, mutant or fragment of the BLAA polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the BLAA polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.

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Lazar et al., Mol Cell Biol. 8:1247-1252, 1988.
Metzler et al., Nature Structural Biol. 1997; 4:527-531.
Blazer et al., J. Immunol., 1996, 157: 3250-3259.

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