Polynucleotides encoding humanized antibodies against human...

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Reexamination Certificate

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C435S007100, C435S252300, C435S069100, C435S455000, C436S512000, C436S513000

Reexamination Certificate

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11073453

ABSTRACT:
A humanized antibody that binds to human 4-1BB and that allows binding of human 4-1BB to a human 4-1BB ligand. In one aspect, the antibody is an IgG4 antibody. Also provided is a method for treating cancer in a subject comprising administering a therapeutically effective amount of the antibody to said subject.

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