Polynucleotides encoding human CTLA-8 related proteins

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 691, 4353201, 4352523, 536 235, C07H 2104, C12N 1519

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active

060748494

ABSTRACT:
Polynucleotides encoding human CTLA-8 related proteins are disclosed. Human CTLA-8 proteins and methods for their production are also disclosed. Methods of treatment using human CTLA-8 proteins, rat CTLA-8 proteins and herpesvirus herpes CTLA-8 proteins are also provided.

REFERENCES:
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Yao et al., J. of Immun. 155(12):5483-5486 (1995).
Fossiez et al., J. of Exp. Med. 183(6):2593-2603 (1996).
Yao et al., Immunity 3(6):811-821 (1995).
Yao et al., Gene 168(2):223-225 (1996).
Yao et al, Immunity vol. 3, 1995, p 811-21.
Nicholas et al, Virolgy vol. 179, pp. 189-200, 1990 (see reg aligment.
Albrechts et al Virolgy 174, p. 533-54, 1990, (see reg aligment).
Fossiez et al., Microbial Evasion and Subversion of Immunity 544:3222 (Abstract) 1995.
Lebecque "Human CTLA-8, a Cytokine That Has Been Hijacked by the T-Cell Transforming Herpes" (AACR Special Conference "Cytokines and Cytokine Receptors" Oct. 14-18, 1995).
Rouvier et al. J. Immunol. 150:5445-5456, 1993.

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