Polynucleotides encoding haemopoietic maturation factor

Details Polynucleotides encoding haemopoietic maturation factor Polynucleotides encoding haemopoietic maturation factor

1994-01-25

1999-07-13

Ulm, John

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 691, 4353201, 4352523, 435325, 536 231, 536 235, C07K 14475, C12N 121, C12N 510, C12N 1512

Patent

active

059225726

ABSTRACT:
Disclosed is a human maturation factor polypeptide and DNA(RNA) encoding such haemopoietic maturation factor polypeptides. Also provided is a procedure for producing such polypeptide by recombinant techniques and antibodies against such polypeptide. Such polypeptides may be combined with a suitable pharmaceutical carrier or diluent to provide diagnostic, therapeutic and/or prophylactic effects against various diseases related to the underexpression of such human haemopoietic maturation factor polypeptide.

REFERENCES:
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Keles, G.E. et al., Expression of Glia Fibrillary Acidic Protein in Human Medulloblastoma Cells Treated with Recombinant.
Glia Maturation Factor Beta, Oncology Research, 4(10):431-437 (1992).
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Bosch, E.P., et al., Axonal Signals Regulate Expression of Glia Maturation Factor Beta in Schwann Cells; An immunohistochemical Study of Injured Sciatic Nerves and Cultureed Schwann Cells, J. Neurosci., 9(10): 3690-98 (1989).
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