Polynucleotides encoding gluS polypeptides of streptococcus pneu

Details Polynucleotides encoding gluS polypeptides of streptococcus pneu Polynucleotides encoding gluS polypeptides of streptococcus pneu

1997-04-18

1999-09-28

Caputa, Anthony C.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 701, 435 711, 4352523, 4353201, 435325, 536 231, 536 237, C12P 2106, C12P 2104, C12N 1500, C07H 2104

Patent

active

059587342

ABSTRACT:
The invention provides gluS polypeptides and DNA (RNA) encoding gluS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gluS polypeptides to screen for antibacterial compounds.

REFERENCES:
R. Calendar et al., "Purification and Physical Characterization of Tyrosyl Ribonucleic Acid Synthetases from Escerichia coli and Bacillus subtilis", Biochemistry, 5(5) pp. 1681-1690 (1966).
J. Hughes et al., "How Does Pseudomonas Fluorescens, the Producing Organism of the Antibiotic Pseudomonic Acid A, Avoid Suicide?", FEBS Letters, 122(2) pp. 322-324 (1980).
Fraser et al., "The Minimal Gene Complement of Mycoplasma gentialium," Science, 270 pp. 397-403 (1995).
Breton et al., "Glutamyl-tRNA Synthetases of Bacillus subtilis 168T and of Bacillus stearothemopilus, " Journal of Biological Chemistry, 265(30) pp. 18348-18255 (1990).
Brun et al., "Closely Spaced and Divergent Promoters for an Aminoacyl-tRNA Synthetase Gene and a tRNA Operon in Escherichia coli," Journal of Molecular Biology, 214 pp. 845-864 (1990).
Lindler et al (J. of Bacteriology vol. 169, No. 7, Jul. 1987, pp. 3199-3208).

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