Polynucleotides encoding gluS polypeptides of streptococcal pneu

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 701, 435 711, 4352523, 4353201, 435325, 536 231, 536 237, C12P 2106, C12P 2104, C12N 1500, C07H 2104

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059768401

ABSTRACT:
The invention provides gluS polypeptides and DNA (RNA) encoding gluS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gluS polypeptides to screen for antibacterial compounds.

REFERENCES:
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Fraser et al., "The Minimal Gene Complement of Mycoplasma gentialium", Science, 270 pp. 397-403 (1995).
Breton et al., Glutamyl-tRNA Synthetases of Bacillus subtills 168T and of Bacillus stearothemopilus:, Journal of Biological Chemistry, 265(30) pp. 18348-18255 (1990).
Brun et al., "Closely Spaced and Divergent Promoters for an Aminoacyl-tRNA Synthetase Gene and a tRNA Operon in Escherichia coli", Journal of Molecular Biology, 214 pp.845-864 (1990).
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