Polynucleotides encoding for fusion proteins with...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C514S012400, C530S324000

Reexamination Certificate

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08063191

ABSTRACT:
This document provides methods and material related to natriuretic polypeptides. For example, substantially pure polypeptides having a natriuretic peptide activity, nucleic acids encoding polypeptides having a natriuretic peptide activity, host cells containing such nucleic acids, and methods for inducing a natriuretic or diuretic activity within a mammal are provided.

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Gene Bank Entry AJ712145 CMPD01 Homo sapiens cDNA clone CMPD10397, mRNA sequence-database entry date Jun. 30, 2004.
Vesely DL, Atrial natriuretic peptides in pathophysiological diseases, Cardiovascular research, 51, 647-658, 2001.
Vesely DL, Natriuretic peptides and acute renal failure, Am. J. Physiol. Renal Physiol. 285: F167-F177, 2003.
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Lebl and Hruby, “Synthesis of cyclic peptides by solid phase methodology,”Tetrahedron Letters, 1984, 25(20):2067-2068.
Burnett et al., “Atrial natriuretic peptide elevation in congestive heart failure in the human,”Science, 1986, 231: 1145-1147.
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PubMed search for atrial natriuretic peptide; Nov. 24, 2009.
PubMed search for brain natriuretic peptide; Nov. 24, 2009.
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