Polynucleotides encoding a protein associated with pancreatic ca

Details Polynucleotides encoding a protein associated with pancreatic ca Polynucleotides encoding a protein associated with pancreatic ca

1996-03-15

1999-12-07

Ulm, John

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

536 235, C12N 1512

Patent

active

059981652

ABSTRACT:
The present invention provides polynucleotides and related reagents which are associated with pancreatic and other cancers. These polynucleotides are designated PANC1A.

REFERENCES:
Caldas et al., "Frequent somatic mutations and homozygous deletions of the p 16 (MTS1) gene in pancreatic adenocarcinoma," Nature Genetics, 8:27-32 (Sep. 1994).
Schutte et al., "Identification by representational difference analysis of a homozygous deletion in pancreatic carcinoma that lies within the BRCA2 region," Proc. Natl. Acad. Sci. USA, 92:5950-5954 (Jun. 1995).
Lisitsyn et al., "Comparative genomic analysis of tumors: Detection of DNA losses and amplification," Proc. Natl. Acad. Sci. USA, 92:151-155 (Jan. 1995).
Mueller-Pillasch et al., "Differential gene expression in pancreatic cancer. Use of an automated approach for the large scale isolation and characterisation of cDNA clones containing differentially expressed sequences," (Aug. 1994) GI 533948 --Abstract only.
Loniello et al., "Diversity among geminiviruses associated with vegetables from Valle del Fuerte, Sinaloa, Mexico," (1994) GI 555403 --Abstract only.

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