Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2007-04-10
2007-04-10
Haddad, Maher M. (Department: 1644)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S455000, C435S252300, C435S320100, C536S023500
Reexamination Certificate
active
10403938
ABSTRACT:
The present invention provides novel polynucleotides encoding BGS-19 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying the novel BGS-19 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
REFERENCES:
patent: WO1999/046281 (1999-09-01), None
patent: WO 00/59942 (2000-10-01), None
patent: WO 01/75067 (2001-10-01), None
patent: WO 02/50105 (2002-06-01), None
patent: WO 02/096452 (2002-12-01), None
patent: WO 03/054152 (2003-07-01), None
patent: WO 03/056027 (2003-07-01), None
patent: WO2004/060270 (2004-07-01), None
Attwood TK. Genomics. The Babel of bioinformatics. Science. 290(5491):471-473, 2000.
Skolnick et al. From genes to protein structure and function: novel applications of computational approaches in the genomic era. Trends Biotechnol. 18(1):34-9, 2000.
Adams, M. et al., “Rapid cDNA sequencing (expressed sequence tags) from a directionally cloned human infant brain cDNA library”. Nature genetics, vol. 4, pp. 373-380 (1993).
Adriaansen, H.J. et al., “Expression of the myeloid differentiation antigen CD33 depends on the presence of human chromosome 19 in human-mouse hybrids”, Ann Hum Genet, vol. 54, pp. 115-119 (1990).
Altschul, Stephen, et al., “Gapped BLAST and PSI-BLAST: a new generation of protein database search programs”, Nucleic Acids Research, vol. 25, No. 17, pp. 3389-3402 (1997).
Avril, T. et al., “Siglec-5 (CD170) Can Mediate Inhibitory Signaling in the Absence of Immunoreceptor Tyrosine-based inhibitory Motif Phosphorylation”, The Journal of Biological Chemistry, vol. 280, No. 20, pp. 19843-19851 (2005).
Balaian L. et al., “Anti-CD33 monoclonal antibodies enhance the cytotoxic effects of cytosine arabinoside and idarubicin on acute myeloid leukemia cells through similarities in their signaling pathways”, Experimental Hematology, vol. 33, pp. 199-211 (2005).
Clark, H.F. et al., “The secreted Protein discovery Initiative (SPDI), a large-scale effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment”, Genome Research, vol. 13, pp. 2265-2270 (2003).
Comish, A.L. et al., “Characterization of Siglec-3, a Novel Glycoprotein Expressed on Myeloid Cells Related to CD33”, Blood, vol. 92, No. 6, pp. 2123-2132 (1998).
Dideberg, O. et al., “Tubulin tyrosine ligase: a shared fold with the glutathione synthetase ADP-forming family”, TIBS, vol. 23, pp. 57-58 (1998).
Egner, W. et al., “Identification of Potent Mixed Leukocyte Reaction-Stimulatory Cells in Human Bone Marrow”, The Journal of Immunology, vol. 150, No. 7, pp. 3043-3053 (1993).
Erickson-Miller, C. et al., “Characterization of Siglec-5 (CD170) expression and functional activity of anti-Siglec-5 antibodies on human phagocytes”, Experimental Hematology, vol. 31, pp. 382-388 (2003).
Falco, M. et al., “Identification and Molecular Cloning of p75/AIRM1, A Novel member of the Sialoadhesin Family that Functions as an Inhibitory Receptor in Human Natural Killer Cells”, J. Exp. Med, vol. 190, No. 6, pp. 793-801 (1999).
Freeman, S.D. et al., “Characterization of CD33 as a New member of the Sialoadhesin Family of Cellular Interaction Molecules”, Blood, vol. 85, No. 8, pp. 2005-2012 (1995).
Garnache-Ottou, F. et al., “Expression of the myeloid-associated marker CD33 is not an exclusive factor for leukemic plasmacytoid dendritic cells”, Blood, vol. 105, No. 3, pp. 1256-1264 (2005).
Grobe, K. et al., “Role of protein kinase C in the phosphorylation of CD33 (Siglec-3) and its effect on lectin activity”, Blood, vol. 99, No. 9, pp. 3188-3196 (2002).
Handgretinger, R. et al., “Expression of an early myelopoietic antigen (CD33) on a subset of human umbilical cord blood-derived natural killer cells.” Immunology Letters, vol. 37, pp. 223-228 (1993).
Kim, H.S. “Assignment1of the human OB binding protein-2 gene (CD33L2) to chromosome 19q13.3 by radiation hybrid mapping”, Cytogenet Cell Genet, vol. 84, pp. 96 (1999).
Liu, H. et al., “Myeloid-lymphoid initiating cells (ML-IC) are highly enriched in the rhodamine-c-kit+CD33+CD38fraction of umbilical cord CD34+cells”, Experimental Hematology, vol. 30, pp. 582-589 (2002).
Mingari, M.C. et al;, “Regulation of myeloid cell proliferation and survival by p75/AIRM1 and CD33 surface receptors”, Progress in Basic and Clinical Immunology, Kluwer Academic/Plenum Publishers pp. 55-61 (2001).
Patel, N. et al., “OB-BP1/Siglec-6”, The Journal of Biological Chemistry, vol. 274, No. 32, pp. 22729-22738 (1999).
Sgroi, D. et al., “A single N-linked Glycosylation Site is Implicated in the Regulation of Ligand Recognition by the I-type Lectins CD22 and CD33”, The Journal of Biological Chemistry, vol. 271, No. 31, pp. 18803-18809 (1996).
Simmons, D. et al., “Isolation of a cDNA encoding CD33, A Differentiation antigen of myeloid progenitor cells1”, The Journal of Immunology, vol. 141, No. 8, pp. 2797-2800 (1988).
Takei, Y. et al., “Molecular cloning of a novel gene similar to myeloid antigen CD33 and its specific expression in placenta”, Cytogenetics Cell Genetics, vol. 78, pp. 295-300 (1997).
Taylor, V. et al., “The Myeloid-specific Sialic Acid-binding Receptor, CD33, Associates with the Protein-tyrosine Phosphatases, SHP-1 and SHP-2”, The Journal of Biological Chemistry, vol. 274, No. 17, pp. 11505-11512 (1999).
Vitale, C. et al., “Engagement of p75/AIRM1 or CD33 inhibits the proliferation of normal or leukemic myeloid cells”, PNAS, vol. 96, No. 26, pp. 15091-15096 (1999).
Walter, R. et al., “Influence of CD33 expression levels and ITIM-dependent internalization on gemtuzumab ozogamicin-induced cytotoxicity”, Blood, vol. 105, No. 3, pp. 1295-1302 (2005).
Wellhausen, S.R. et al., “CD33:Biochemical and biological characterization and evaluation of clinical relevance”, J Biol Regul Homeost Agents, vol. 16, pp. 139-143 (2002).
Whitney, G. et al., “A new siglec family member, siglec-10, is expressed in cells of the immune system and has signaling properties similar to CD33”, Eur. J. Biochem. vol. 268, pp. 6083-6096 (2001).
Williams, A. et al., “The Immunoglobulin superfamily-Domains for cell surface recognition1,2”, Ann. Rev. Immunol. vol. 6, pp. 381-405 (1988).
Yousef, G. et al., “Genomic organization of the siglec gene locus on chromosome 19q13.4 and cloning of two new siglec pseudogenes”, Gene, vol. 286, pp. 259-270 (2002).
NCBI Entrez Accession No. AA341128 (gi:1993613) Adams, M.D. et al., Apr. 21, 1997.
NCBI Entrez Accession No. AAH39008 (gi:24658685) Strausberg, R. Nov. 6, 2002.
NCBI Entrez Accession No. AAQ88502 (gi:37181376) Clark, H.F. et al. Oct. 3, 2003.
NCBI Entrez Accession No. AC011452 (gi:9885999) DOE Joint Genome Institute and Stanford Human Genome Center. Aug. 23, 2000.
NCBI Entrez Accession No. AY358135 (gi:3718375) Clark, H.F. et al. Oct. 3, 2003.
NCBI Entrez Accession No. BF205116 (gi:11098702) NIH-MGC hhtp://mgc.nci.nih.gov/. Nov. 6, 2000.
NCBI Entrez Accession No. BF308356 (gi:11255555) NIH-MGC hhtp://mgc.nci.nih.gov/. Nov. 21, 2000.
NCBI Entrez Accession No. BF969219 (gi:12336434) NIH-MGC hhtp://mgc.nci.nih.gov/. Jan. 22, 2001.
NCBI Entrez Accession No. BG826221 (gi:14173808) NIH-MGC hhtp://mgc.nci.nih.gov/. May 22, 2001.
NCBI Entrez Accession No. B1518708 (gi:15343500) NIH-MGC hhtp://mgc.nci.nih.gov/. Aug. 29, 2001.
NCBI Entrez Accession No. NP—001763 (gi:50727000) Walter, R.B. et al., Sep. 24, 2005.
NCBI Entrez Accession N
Chen Jian
Feder John N.
Lee Liana M.
Wu Shujian
Bristol--Myers Squibb Company
D'Amico Stephen C.
Haddad Maher M.
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