Polynucleotides encoding a 6-phosphogluconolactonase...

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...

Reexamination Certificate

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C435S041000, C435S069100, C435S183000, C435S195000, C435S196000, C435S197000, C435S252300, C435S320100, C536S023200

Reexamination Certificate

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09602740

ABSTRACT:
Isolated nucleic acid molecules, designated sugar metabolism and oxidative phosphorylation (SMP) nucleic acid molecules, which encode novel SMP proteins fromCorynebacterium glutamicum, are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing SMP nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated SMP proteins, mutated SMP proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound fromC. glutamicumbased on genetic engineering of SMP genes in this organism.

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