Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2003-06-11
2010-12-28
Robinson, Hope A (Department: 1652)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S006120, C435S320100, C435S252000, C530S350000
Reexamination Certificate
active
07858340
ABSTRACT:
The present invention relates to polynucleotide molecules comprising nucleotide sequences encoding an aveC gene product, which polynucleotide molecules can be used to alter the ratio or amount of class 2:1 avermectins produced in fermentation cultures ofS. avermitilis. The present invention further relates to vectors, host cells, and mutant strains ofS. avermitilisin which the aveC gene has been inactivated, or mutated so as to change the ratio or amount of class 2:1 avermectins produced.
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Chen Yan
Gustafsson Claes
Krebber Anke
Minshull Jeremy
Raillard Sun Ai
Misiak Paul M.
Pfizer Inc.
Pfizer Products Inc.
Robinson Hope A
Wootton Thomas A.
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