Polynucleotides active as inducers of interferon production in l

Drug – bio-affecting and body treating compositions – Lymphokine

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536 28, A61K 4504

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active

041247027

ABSTRACT:
Polynucleotides which are multistranded are active as inducers of interferon production in living animal cells. They may be:

REFERENCES:
patent: 3629235 (1971-12-01), Lampson et al.
Finter Interferons, published by North-Holland Pub. Co., Amsterdam, 1966, pp. 36, 37 and 256.
Hilleman Arch. Intern. Med., vol. 126, pp. 114, 119, and 120, (1970).
Lampson et al., Proc. Nat. Acad. Sci., vol. 58, pp. 782-789 (1967).
Langridge et al., Proc. Nat. Acad. Sci., vol. 52, pp. 114-119 (1964).
Weissmann et al., Proc. Nat. Acad. Sci., vol. 51, pp. 682-690 (1964).
Iglewski et al., J. Virol., vol. 1, pp. 302-307, Apr. 1967.
Haselkorn et al., J. Biol. Chem., vol. 236, pp. 2738-2745 (1961).
Rotem Israel, J. Exper. Med., vol. 11, pp. 174-178 (1963).
Lancet, Mar. 6, 1965, pp. 505 and 506.

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