Polynucleotide sequence encoding human multiple endocrine neopla

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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536 231, 4352523, 4353201, C12N 1511, C12N 1563, C12N 121, C12N 1500

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059726490

ABSTRACT:
The invention provides a human multiple endocrine neoplasia type 1 protein (MEND1) and polynucleotides which identify and encode MEND1. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of MEND1.

REFERENCES:
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Tao et al (J. Immunol, 143: 2595-2601), 1989.
Hillier et al (Genbank Acession # H14300, NIPg879120), 1995.
Emmert-Buck, M.R. et al., "Laser capture microdissection." Science (1996) 274:998-1001.
Chandrasekharappa, S. C. et al., "Positional Cloning of the Gene for Multiple Endocrine Neoplasia-Type 1." Science(1997) 276:404-407. (GI 1945387).
Chandrasekharappa, S.C. et al. (GI 1945386), GenBank Sequence Database (Accession U93236), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894.

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