Polynucleotide molecule from Haematococcus pluvialis encoding a

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase

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435325, 435410, 435423, 4352523, 43525233, 435320, 435183, 536 232, C12N 902

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059167912

ABSTRACT:
The present invention relates, in general, to a biotechnological method for production of (3S,3'S) astaxanthin. In particular, the present invention relates to a peptide having a .beta.-C-4-oxygenase activity; a DNA segment coding for this peptide; a RNA segments coding for this peptide; a recombinant DNA molecule comprising a vector and the DNA segment; a host cell or organism containing the above described recombinant DNA molecule or DNA segment; and to a method of biotechnologically producing (3S,3'S) astaxanthin or a food additive containing (3S,3'S) astaxanthin, using the host.

REFERENCES:
Armstrong, G., "Eubacteria Show Their True Colors: Genetics of Carotenoid Pigment Biosynthesis from Microbes to Plants" Journal of Bacteriology vol. 176 No. 16 (Aug. 1994).
Ausich, R. "Production of Carotenoids by Recombinant DNA Technology" Pure & Appl. Chem. vol. 66 No. 5 pp. 1057-1062 (1994).
Meyers, S. "Developments in World Aquaculture, feed formulations, and Role of Carotenoids" Pure & Appl. Chem. vol. 66 No. 5 pp. 1069-1076 (1994).
Lotan, T. et al, "Cloning and Expression in Escherichia coli of the Gene Encoding .beta.-C-4 Oxygenase, that Converts .beta.-Carotene to the Ketocarotenoid canthaxanthin in Haematococcus Pluvialis" FEBS Letters 364 pp. 125-128 (1995).
Yokoyama, A. et al, "Composition and Presumed Biosynthetic Pathway of Carotenoids in the astaxanthin-producing bacterium Agrobacteriom Aurantiacum" FEMS Micribiology Letters 128 pp. 139-144 (1995).
Sandmann, G., "Carotenoid Biosynthesis in Microorganisms and Plants" Eur. J. Biochem 223, 7-24 (1994).
Andrews, A. et al "Carotenoids of Phaffia Rhodozyma, a Red-Pigmented Fermenting Yeast", Phytochemistry vol. 15 pp. 1003-1007.
Misawa, N. et al, "Canthaxanthin Biosynthesis by the Conversion of Methylene to Keto Groups in a Hydrocarbon-Carotene by a Single Gene", Biochemical and Biophysical Research Communications vol. 209 No. 3 pp. 867-876 (Apr. 1995).
Hladik, F. et al, "Carotenoid Content of Photosystem1-Pigment-Protein Complexes of the Cyanobacterium Snechococcus Elongatus" Photosynthetica 23 (4):603-616 (1989).
Andrews, A. et al., "Animal Carotenoids. 9 On the Absolute Configuration of Asthaxanthin and Actinioerythrin" Acta Chem. Scan. B 28 No. 7 pp. 730-736 (1974).
Armstrong, G. et al "Evolutionary Conservation and Strucural Simalarities of Carotenoid Biosynthesis Gene Products from Photosynthetic and Nonphotosynthetic Organisms" Molecular and Cell Biology, pp. 297-311.
Armstrong, G. et al "Nucleotide Sequence, Organization, and Nature of the Protein Products of the Carotenoid Biosynthesis Gene Cluster of Rhodobacter Capsulatus" Mol. Gen. Genet 216:254-268 (1989).
Bartley, G. et al, "Molecular Cloning Expression in Photosynthetic Bacteria of a Soybean cDNA coding for Phytoene Desaturase, an Enzyme of the Carotenoid Biosynthesis Pathway" Proc. Natl. Acad. Sci. USA vol. 88 pp. 6532-6536 (1991).
Bassi, R. et al, "Carotenoid-Binding Proteins of Photosystem II" Eur J Biochem 212, 297-303 (1993).
Weiss, G. et al "Stabilization and Reconstitution of the Membrane-Bound Carotenogenic Enzymes of Daffodil Chromoplasts" Eur J. Biochem 153, 341-346 (1985).
Beyer, P. et al "Molecular Oxygen and the State of Geometric Isomerism of Intermediates are Essential in the Carotene Desaturation and Cyclization Reactions in Daffodil Chromoplasts" Eur. J. Biochem. 184, 141-150 (1989).
Breton, J. et al, "Orientation of the Pigments in Photosystem II: low-temperature linear-dichroism study of a core particle and of its chlorophyll-protien subunits isolated from Snechococcus sp." Biochimica et Biophysica Acta 892 pp. 99-107 (1987).
Camara, B., "Plant Phytoene Synthase Complex: Component Enzymes, Immunology, and Biogenesis", Methods in Enzymology, vol. 214 pp. 352-365 (1993).
Camara, B. et al, "Demonstration and Solubilization of Lycopene Cyclase from Capsicum Chromoplast Membranes", Plant Physiol. 80, pp. 172-174 (1986).
de Loura, I. et al, "The Effects of Nitrogen Deficiency on Pigments and Lipids of Cyanobacteria", Plant Physiol. 83, pp. 838-843 (1987).
Carattoli, A. et al, "The Neurospora crassa Carotenoid Biosynthetic Gene (Albino 3) Reveals Highly Conserved Regions among Prenyltransferases", The Jour. of Biol. Chem. vol. 266 No. 9 pp. 5854-5859 (1991).
Chamovitz, D. et al, "Molecular Cloning and Expression in Escherichia coli of a Cyanobacterial Gene Coding for Phytoene Synthase, a carotenoid Biosynthesis Enzyme", FEBS vol. 296 No. 3 pp. 305-310 (1992).
Chamovitz, D. et al, "Cloning a Gene Coding for Norflurazon Resistance in Cyanobacteria", Z. Naturforsch, 45c pp. 482-486 (1990).
Chamovitz, D. et al, "The Molecular Basis of Resistance to the Herbicide Norfluazon" Plant Molecular Biology 16:967-974 (1991).
Chamovitz, D. et al, "Molecular and Biochemical Characterization of Herbicide-Resistant Mutants of Cyanobacteria Reveals that Phytoene Desaturation is a Rate-Limiting Step in Carotenoid Biosynthesis", Jour. Biol. Chem. vol. 268 No. 23 pp. 17348-17353 (1993).
Clarke, I. et al "Carotene Biosynthesis with Isolated Photosynthetic Membranes", FEBS Letters vol. 140 No. 2 (Apr. 1982) pp. 203-206.
Cogdell, R., "The Function of Pigments in Chloroplasts", Plant Pigments, Academic Press, pp. 183-230 (1988).
Cogdell, R. et al "Functions of Carotenoids in Photosynthesis", Metabolism, Academic Press, pp. 185-193 (1991).
Cogdell, R. et al "How Carotenoids Function in Photosynthetic Bacteria", Biochemica et Biophsyica Acta, 895, pp. 63-79 (1987).
Cunningham, Jr., et al "Cloning abd Functional Expression in Escherichia coli of a cyanobacterial Gene for Lycopene cyclase, the enzyme that Catalyzes the biosynthesis of .beta.-Carotene", FEBS vol. 328 No. 1,2 pp. 130-138 (1993).
Cunningham , Jr., F. et al "Molecular Structure and Enzymatic Function of Lycopene Cyclase from the Cyanobacterium Synechococcus sp Strain PCC7942", The Plant Cell, vol. 6 pp. 1107-1121 (Aug. 1994).
De Las Rivas, J. et al "Two coupled .beta.-Carotene Molecules Protect P680 from Photodamage in Isolated Photosystem II Reaction Centers", Biochemica et Biophsyica Acta, 1142 pp. 155-164 (1993).
Demmig-Adamas, B. Carotenoids and Photoprotection in Plants: A Role for the Xanthophyll Zeaxanthin Biochemica et Biophsyica Acta, 1020 pp. 1-24 (1990).
Fraser, P. et al "Purification and Reactivation of Recombatant Synechococcus Phytoene Desaturate From an Everexpressing Strain of Edcherichia Coli", Biochem. J., 291: pp. 687-692 (1993).
Gounaris, K. et al, "Isolation and Characterisation of a D1/D2/Cytochrome b-559 Complex from Synechocystis 6803", Biochemica et Biophysica Acta, 973 pp. 296-301 (1989).
Hirschberg, J. et al, "Isolation and Characterisation of Herbicide Resistant Mutants in the Cyanobacterium Synechococcus R2", Z. Naturforsch, 42c, pp. 758-761 (1987).
Hugueney, P. et al, "Characterization and Molecular Cloning of a Flavoprotein Catalyzing the Synthesis of Phytofluene and C-Carotene in Capsicum Chromoplasts", Eur. J. Biochem., 209, pp. 399-407 (1992).
Humbeck, K. et al, "Evidence for an Essential Role of Carotenoids in the Assembly of an Active Photosystem II" Planta, 179, pp. 242-250 (1989).
Demming-Adams, B. et al, "The Carotenoid Zeaxanthin and "High-Energy-State Quenching" of Chlorophyll Fluorescence", Photosynthesis Research, 25 pp. 187-197 (1990).
Demming-Adams, B. et al, "Differences in the Susceptibility to ti Light Stress on Two Lichens forming a phycosymbiodeme, One Partner Possessing One Lacking the Xanthopyll Cycle", Oecologia, 84: pp. 451-456 (1990).
Demming-Adams, B. et al, "Photoprotection and Other Responses of Plants to High Light Stress", Annu. Rev. Plant Physiol. Plant Mol. Biol. 43: pp. 559-626 (1992).
Dogbo, O. et al, "Purification of Isopentenyl Pyrophosphate Isomerase and Geranylgeranyl Pyrophosphate Synthase from Capsicum Chromoplasts by Affinity Chromatography", Biochemica et Biophysica Acta, 920, 140-148 (1987).
Frank, H. et al "Carotenoids in Photosynthesis: Structure and Photochemistry", Pure & Appl. Chem. vol. 63 No. 1 pp. 109-114 (1991).
Hundle, B. et al "Carotenoids of Erwinia Herbicola and Escherichia Coli HB101 Strain Carrying the Erwinia Herbicola Carotenoi

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