Polynucleotide encoding lysyl-tRNA synthetase from Zea mays

Multicellular living organisms and unmodified parts thereof and – Method of introducing a polynucleotide molecule into or...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S194000, C435S069100, C435S350000, C435S320100, C435S252300, C435S325000, C435S410000, C435S419000, C435S183000, C435S231000, C435S193000, C800S295000, C536S023200

Reexamination Certificate

active

07038108

ABSTRACT:
This invention relates to isolated nucleic acid fragments encoding aminoacyl-tRNA synthetases and particulary lsoleucyl-, lysyl-, phenylalanyl- and prolyl-tRNA synthetases fromZea mays, Oryza sativa, Glycine max and Tritium aestivum. The invention also relates to the construction of a chimeric gene encoding all or a portion of the aminoacyl-tRNA synthetase, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the aminoacyl-tRNA synthetase in a transformed host cell.

REFERENCES:
patent: 5759833 (1998-06-01), Shiba et al.
Giritch et al. A root-specific iron-regulated gene of tomato encodes a lysyl-tRNA-synthetase-like protein. Eur. J. Biochem. (1997) 244(2): 310-317.
GenBank Accession No. AF125574. Arabidopsis thaliana lysyl-tRNA synthetase mRNA, complete cds. Mar. 3, 1999.
Genbank Accession No. X94451. L. esculentum mRNA for lysyl-tRNA synthetase. Apr. 8, 1997.
Terada et al. Functional convergence of two lysyl-tRNA synthetases with unrelated topologies. Nature Structural Biology (2002) 9:257-262.
Nichols et al. Human iso-leucyl-tRNA synthetase:sequence of the cDNA, alternative mRNA splicing, and the characteristics of an unusually long C-terminal extension. Gene, 1995, vol. 155:299-304.
GenBank Accession No. U04953, dated Oct. 31, 1995.
National Center for Biotechnology Information General Identifier No. 135134, Feb. 1, 1996.
Duane W. Martindale et al., “Isolation and Complete Sequence of the Yeast isoleucyl-tRNA Synthetase gene (ILSI)”, Curr. Genet. 15(2), 99-106, (1989).
Uwe Englisch et al., Biol. Chem. Hoppe-Seyler, “Structure of the Yeast Isoleucyl-tRNA Synthetase Gene (ILSI)”, vol. 368 (8), 971-979 (Aug. 1987).
Brigitte Obermaier et al., “Sequence Analysis of a 78 6 kb Segment of the Left end of Saccharomyces cerevisiae Chromosome II”, Yeast, vol. 11:1103-1112 (1995).
National Center for Biotechnology Information General Identifier No. 730870, Nov. 1, 1997.
Kiyotaka Shiba et al., “Human cytoplasmic isoleucyl-tRNA synthetase: Selective divergence of the anticodon-binding domain and acquisition of a new structural unit”, Proc. Natl. Acad. Sci. 91 (16), 7435-7439, (Aug. 1994).
National Center for Biotechnology Information General Identifier No. 4504555, Mar. 19, 1999.
Dharam P. Singal et al., “Human Y-box transcription factors: sequences of two new YB-I alleles”, Gene 154 (2), 299-300 (1995).
National Center for Biotechnology Information General Identifier No. 4325324, Mar. 3, 1999.
National Center for Biotechnology Information General Identifier No. 3983103, Dec. 9, 1998.
National Center for Biotechnology Information General Identifier No. 172947, Apr. 27, 1993.
Ambaliou Sanni et al., “Structure and Expression of the Genes Encoding the a and B subunits of Yeast Phenylalanyl-tRNA Synthetase”, J. Biol. Chem. 263, 15407-15415 (1988).
National Center for Biotechnology Information General Identifier No. 4758294, May 7, 1999.
Radegunde Fett et al., “The Primary Structure of Human Glutaminyl-tRNA Synthetase”, J. Biol. Chem. 266(3), 1448-1455 (1991).
Neidhartdt, et al, “Function and Regulation of AminoAcyl-tRNA Synthetases in Prokaryotic and Eukaryotic Cells”, Annu. Rev. Microbiology, pp. 215-250, 1975.
Jerzy Zon et al., “Novel Phenylalanine Analogues as Putatitive Inhibitors of Enzymes Acting on Phenylalanine”, Phytochemistry, vol. 27, No. 3 pp. 711-714 (1988).
Donald Heacock et al., “Synthesis and Aminoacyl-tRNA Synthetase Inhibitory Activity of Prolyl Adenylate Analogs”, Bioorganic Chemistry 24, 273-289 (1996).
Arnez, John G. et al., “Structural and functional considerations of the aminoacylation reaction,” TIBS, Jun. 1997, 22:211-216.
Desogus, Gianluigi et al., “Active Site of Lysyl-tRNA Synthetase: Structural Studies of the Adenylation Reaction,” Biochemistry, 2000, vol. 39:8418-8425.
Albert L. Lehninger, et al.; “Principles in Biochemistry with an Extended Discussion of Oxygen-Binding Proteins”, 1993, 912-913, Worth Publishers, New York, US.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Polynucleotide encoding lysyl-tRNA synthetase from Zea mays does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Polynucleotide encoding lysyl-tRNA synthetase from Zea mays, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polynucleotide encoding lysyl-tRNA synthetase from Zea mays will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3557709

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.