Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1997-07-11
2000-06-27
Teng, Sally P.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
536 235, 4352523, 43525411, 4353201, 435325, C12N 1512
Patent
active
060805587
ABSTRACT:
The invention provides a new human growth regulator protein (GRREG) and polynucleotides which identify and encode GRREG. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of GRREG.
REFERENCES:
Liebermann, D.A. et al., "Differentiation Primary Response Genes and Proto-oncogenes as Positive and Negative Regulators of Terminal Hematopoietic Cell Differentiation", Stem Cells, 12: 352-369 (1994).
Ron, D. et al., "CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and Functions as a dominant-negative inhibitor of gene transcription", Genes Dev., 6-439-453 (1992).
Smith, M.L. et al., "Interaction of the p53-Regulated Protein Gadd45 with Proliferating Cell Nuclear Antigen", Science, 266:1376-1380 (1994).
Lord, K.A. et al., "Sequence of MyD116 cDNA: a novel myeloid differentiation primary response gene induced by IL6", Nucleic Acids Res., 18: 2823 (1990) (GI 530341).
Lord, K.A. et al., "Dissection of the Immediate Early Response of Myeloid Leukemia Cells to Terminal Differentiation and Growth Inhibitory Stimuli", Cell Growth Differen., 1: 637-645 (1990).
Zhan, Q. et al., "The gadd and MyD Genes Define a Novel Set of Mammalian Genes Encoding Acidic Proteins That Synergistically Suppress Cell Growth", Molec. Cell. Biol., 14: 2361-2371 (1994).
Zhan, Q., (Direct Submission), GenBank Sequence Database (Accession L28147), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 452489; GI 452490).
Lord, K.A. et al., (Direct Submission), GenBank Sequence Database (Accession X51829), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 53040; GI 53041).
Bandman Olga
Corley Neil C.
Lal Preeti
Shah Purvi
Billings, Esq. Lucy J.
Incyte Pharmaceuticals Inc.
Muenzen, Esq. Collette C.
Teng Sally P.
LandOfFree
Polynucleotide encoding human growth regulator protein does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Polynucleotide encoding human growth regulator protein, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polynucleotide encoding human growth regulator protein will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1783181