Polynucleotide encoding growth differentiation factor-12

Details Polynucleotide encoding growth differentiation factor-12 Polynucleotide encoding growth differentiation factor-12

1994-07-13

1998-11-03

Ulm, John

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435 691, 4352402, 4352523, 4353201, 530399, 935 11, 935 27, 935 32, 935 66, 935 70, 935 72, C12N 1518, C04K 14475

Patent

active

058310541

ABSTRACT:
Growth differentiation factor-12 (GDF-12) is disclosed along with its polynucleotide sequence and amino acid sequence. Also disclosed are diagnostic and therapeutic methods of using the GDF-12 polypeptide and polynucleotide sequences.

REFERENCES:
Sampath et al. (1993) Proc. Natl. Acad. Sci. U.S.A., vol. 90, pp. 6004-6008.
Expression of growth/differentiation factor 1 in the nervous system: Conversation of a bicistronic structure Se-Jin Lee, Proc. Natl. Acad. Sci. USA., 88:4250-4254, May 1991.
GDF-3 and GDF-9: Two New Members of the Transforming Growth Factor-.beta.Superfamily Containing a Novel Pattern of Cysteines*--McPherron, et al., The Journal of Biological Chemistry, #5, 268:3444-3449, Feb. 15, 1993.
Identification of Novel Member (GDF-1) of the Transforming Growth Factor-.beta.Superfamily Se-Jin Lee, Mol. Endo, No. 7, 4:1034-1039, 1990.

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