Polynucleotide encoding G-protein coupled receptor (H7TBA62)

Details Polynucleotide encoding G-protein coupled receptor (H7TBA62) Polynucleotide encoding G-protein coupled receptor (H7TBA62)

1997-10-27

1999-09-21

Mertz, Prema

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

536 231, 536 235, 536 243, 536 2431, 435 712, 4352523, 4353201, 435470, 43525411, 435325, C12N 1512, C12N 510, C12N 1563, C07K 14705

Patent

active

059553090

ABSTRACT:
H7TBA62 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing H7TBA62 polypeptides and polynucleotides in the design of protocols for the treatment of infections such as bacterial, fungal protozoan and viral infections, particularly infections caused by HIV-1 or HIV-2; pain; cancers; anorexia; bulimia; asthma; Parkinson's disease; acute heart failure; hypotension; hypertension; urinary retention; osteoporosis; angina pectoris; myocardial infarction; ulcers; asthma; allergies; benign prostatic hypertrophy; and psychotic and neurological disorders, including anxiety, schizophrenia, manic depression, delirium, dementia, severe mental retardation and dyskinesias, such as Huntington's disease or Gilles dela Tourett's syndrome, among others and diagnostic assays for such conditions.

REFERENCES:
patent: 5556780 (1996-09-01), Dzau et al.
patent: 5591620 (1997-01-01), Musters et al.
George et al. Macromolecular Sequencing and Synthesis, Selected Methods and Applications, Alan R. Liss, Inc., Chptr. 12, pp. 127-149,1988.
GenBank Accession #P31391 Jul. 1, 1993. Xu et al.
GenBank Accession #P25106 May 1, 1992 Sacedhanan et al.
GenBank Accession #L07062 Aug. 20, 1993 Connen et al.
GenBank Accession #U03642 June 11, 1996 O'Dowd et al.
EST #1463525, Mar. 19, 1997.

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