Polynucleotide capturing support for capturing, eluting and coll

Details Polynucleotide capturing support for capturing, eluting and coll Polynucleotide capturing support for capturing, eluting and coll

1996-10-10

1998-10-06

Horlick, Kenneth R.

Chemistry: molecular biology and microbiology

Apparatus

Including measuring or testing

422 681, 422 8201, 422101, 422104, C12Q 168, B01L 1100

Patent

active

058175067

ABSTRACT:
A polynucleotide capturing support for capturing, eluting and collecting a plurality of target polynucleotides in a sample solution. The polynucleotide capturing support includes a substrate having a plane surface and a plurality of cells which immobilize individually different probes complementary to a plurality of target polynucleotides, and form at different regions on said plane surface of said substrate. The support includes a plurality of first electrodes which supply an electric field to each of the cells. The first electrodes are capable of eluting the target polynucleotides hybridized to the probes from each of the cells individually. The support also includes a plurality of second electrodes arranged between the adjacent cells on the surface of the substrate, and an electrode field is supplied to each of the second electrodes. A means for switching an electric field is provided for and applied to at least one of the first electrodes thereby effecting the elution and separation of the target polynucleotides. The target polynucleotides hybridize with the probes when the sample solution contacts the surface of the substrate.

REFERENCES:
patent: 4859302 (1989-08-01), Alfenito
patent: 4945045 (1990-07-01), Forrest et al.
patent: 5089387 (1992-02-01), Tsay et al.
patent: 5217591 (1993-06-01), Gombocz et al.
patent: 5532128 (1996-07-01), Eggers et al.

Affiliated with

Also associated with

Rating

Polynucleotide capturing support for capturing, eluting and coll does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Polynucleotide capturing support for capturing, eluting and coll, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polynucleotide capturing support for capturing, eluting and coll will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-76170