Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1996-12-30
2000-10-31
Kight, John
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514319, 514321, 514357, 514408, 514422, 514426, 540484, 540596, 540611, 540612, 546197, 546206, 546237, 548400, 548526, 548529, A01N 4346, A01N 4336, C07D21120, C07D22300
Patent
active
061403210
ABSTRACT:
Donepezil hydrochloride, 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine hydrochloride, is provided here in the form of four polymorphs which are stable against heat and humidity in the pharmaceutical use. They can be industrially produced. They are specified by peaks in X-ray powder diffraction pattern and absorption peaks in infrared absorption spectra in potassium bromide.
REFERENCES:
patent: 4895841 (1990-01-01), Sugimoto et al.
Iimura et al, Chemical Abstract vol. 117 No. 191509, "Prep. of Optically Active Indanone Der. as Acetylcholinesterase Inhibitors" (1992).
Imai Akio
Ishihama Yasushi
Kajima Takashi
Ohtsuka Akiyo
Tanaka Tomohide
Covington Raymond
Eisai Co. Ltd.
Kight John
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