Polymorphisms in human mitochondrial DNA

Details Polymorphisms in human mitochondrial DNA Polymorphisms in human mitochondrial DNA

1997-05-14

2008-03-04

Zhou, Shubo (Joe) (Department: 1631)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S006120, C435S252300, C435S320100, C435S325000, C536S023100

Reexamination Certificate

active

07339049

ABSTRACT:
The invention provides novel human mitochondrial polymorphisms, and probes and primers for detecting the same. Detection of such polymorphisms is useful in a variety of fields such as forensic analysis, epidemiology and preventive medicine.

REFERENCES:
patent: 5206137 (1993-04-01), Ip et al.
patent: 5292639 (1994-03-01), Beitz et al.
patent: 5468610 (1995-11-01), Polymeropoulos et al.
patent: 5494794 (1996-02-01), Wallace
patent: 5565523 (1996-10-01), Parker et al.
patent: 5760205 (1998-06-01), Parker et al.
patent: 5840493 (1998-11-01), Davis et al.
Anderson et al., Nature, vol. 290, pp. 457-465, 1981.
1990 Sigma Catalog [Publ. by Sigma Chemical Company, P.O. Box 14508, St. Louis, Missouri, USA.] p. 776, 1990.
Stoneking et al., American Journal of Human Genetics, vol. 48, pp. 370-380, 1991.
Aquadro et al., Genetics, vol. 103, pp. 287-312, 1983.
Chee, Mark et al., “Accessing Genetic Information With High-density DNA Arrays”,Science, (Oct. 25, 1996) vol. 274, pp. 610-614.
Curriden, Mark, “A New Evidence Tool”,ABA Journal(Nov. 1996) p. 18.
Davis, Robert E. et al., “Mutations In Mitochondrial CytochromecOxidase Genes Segregate With Late-Onset Alzheimer Disease”,Proc. Natl. Acad. Sci. USA, (Apr. 1997) vol. 94, pp. 4526-4531.
Fan, Jian-Bing et al., “Screening the Human Genome for Single-nucleotide Polymorphisms by Hybridization to High-density Oligonucleotide Arrays”, Mutation Detection '97, 4th International Workshop (May 29-Jun. 2, 1997, Brno, Czech Rebublic) 1 page.
Greenberg, Barry D. et al., “Intraspecific Nucleotide Sequence Variability Surrounding the Origin of Replication in Human Mitochondrial DNA”, (1983)Gene, vol. 21, pp. 33-49.
Kwok, Pui-Yan et al., “Increasing the Information content of STS-Based Genome Maps: Identifying Polymorphisms in Mapped STSs”,Genomics, (1996) vol. 31, Article No. 0019, pp. 123-126.
Wallace, Douglas C., “Diseases of the Mitochondrial DNA”,Annu. Rev. Biochem.(1992) vol. 61, pp. 1175-1212.
Ginther et al., “Identifying individuals by sequencing mitochondrial DNA from teeth.” Nature Genetics, 2:135 (Oct. 1992).
Greenberg et al., “Intraspecific nucleotide sequence variability surrounding the origin of replication in human mitochondrial DNA,” Gene 21(1-2):33 (1983).
Howell et al., “Mitochondrial gene segregation in humans: is the bottleneck always narrow?” Human Genetics, 90:117 (1992).
Howell et al., “When does bilateral optic atrophy become Leber hereditary optic atrophy?” American Journal of Human Genetics, 53:959 (1993).
Hutchin et al., “A molecular basis for human hypersensitivity to aminoglycoside antibiotics,” NAR 21(18):4174 (1993).
Ikebe et al., “Point mutations of mitochondrial genome in PArkinson's disease,” Molecular Brain Research 28(2):281 (1995).
Isenberg and Moore, “Mitochondrial DNA Analysis at the FBI Laboratory,” Forensic Science Communications, vol. 1, No. 2 (Jul. 1999).
Johns and Neufeld, “Pitfalls in the molecular genetic diagnosis of Leber hereditary optic neuropathy (LHON),” American Journal of Human Genetics, 53 (4):916 (1993).
Marzuki et al., “Normal variants of human mitochondrial DNA and translation products: building a reference data base,” Human Genetics, 88 (2):139 (1991).
Mehta, et al., “A new genetic polymorphism in the 16S ribosomal RNA gene of human mitochondrial DNA,” Annals of Human Genetics, 53 (Pt. 4):303 (1989).
Moraes, et al., “Two novel pathogenic mitochondrial DNA mutations affecting organelle number and protein synthesis. Is the tRNA Leu(UUR) gene an etiologic hot spot?” J. of Clinical Investigation, 92(6):2906 (1993).
Ozawa et al., “Distinct clustering of point mutations in mitochondrial DNA amoung patients with mitochondrial encephalomyopathies and with Parkinson's disease,” BBRC, 176 (2):938 (1991).
Ozawa et al., “Patients with idiopathic cardiomyopathy belong to the same mitochondrial gene family of Parkinson's disease and mitochondrial encephalomyopathy,” BBRC 177(1):518 (1991).
Petruzzella et al., “Is a point mutation in the mitochondrial ND2 gene associated with Alzheimer's disease?” BBRC 186:491 (1992).
Prezant et al., “Mitochondrial ribosomal RNA mutation associated with both antibiotic-induced and non-syndromic deafness,” Nature Genetics, 4 (3):289-294(1993).
Reid et al., “Complete mtDNA sequence of a patient in a maternal pedigree with sensorineural deafness,” Human Molecular Genetics, 3(8):1435 (1994).
Ruvolo et al., Mitochondrial COII sequences and modern huiman origins, Molecular Biology and Evolution, 10:1115 (1993).
Seneca et al., “Importance of sequence analysis in the NARP syndrome,” J. Inherited Metabolic Disorders, 18 (1):97 (1995).
Tanaka and Ozawa, “Strand asymmetry in human mitochondrial DNA mutations,” Genomics, 22(2):327 (1994).
Graven et al., “Evolutionary Correlation between Control Region Sequence and Restriction Polymorphismns in the Mitochondrial Genome of a Large Senegalese Mandenka Sample,”Mol. Biol. Evol., 12(2):334-345.
Lipshutz et al., “Using Oligonucleotide Probe Arrays To Access Genetic Diversity,”BioTechniques, 19(3):442-447 (1995).
Petros et al., “mtDNA mutations increase tumorigenicity in prostate cancer,”PNAS, 102(3):719-824 (2005).

Affiliated with

Also associated with

Rating

Polymorphisms in human mitochondrial DNA does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Polymorphisms in human mitochondrial DNA, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polymorphisms in human mitochondrial DNA will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3977702