Polymorphisms in a microsatellite region of a glucocorticoid rec

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 912, 536 231, 536 241, 536 2431, 536 2433, C12Q 168, C12P 1934, C07H 2104

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061565105

ABSTRACT:
A method of diagnosis of a disease, Syndrome X in one embodiment, in an individual comprises determining the genotype of a microsatellite region of a glucocorticoid receptor gene in said individual. A method of identifying an individual predisposed or susceptible to the disease comprises determining the genotype of a microsatellite region of a glucocorticoid receptor gene in said individual. Methods of treatment and therapy for diseased or predisposed or susceptible individuals are provided, together with apparatus for carrying out the diagnosis.

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