Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1989-04-27
1992-02-25
Wax, Robert A.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
536 27, 935 77, 935 78, C12Q 168, C07H 1512, C12N 1500
Patent
active
050913026
ABSTRACT:
Isolated polynucleotide molecules, and peptides encoded by those molecules, can be used in the analysis of alloantigen phenotypes, as well as in diagnostic and therapeutic applications relating to human platelet Pl.sup.A polymorphism. In this vein, a method for typing blood cell and platelet membrane glycoproteins entails an analysis of amplified cDNA, encoded by platelet and red blood cell mRNA.
REFERENCES:
patent: 4351901 (1982-09-01), Bahl
patent: 4582788 (1986-04-01), Erlich
patent: 4683194 (1987-07-01), Saiki
patent: 4683195 (1987-07-01), Mullis et al.
patent: 4683195 (1987-07-01), Mullis
patent: 4772549 (1988-09-01), Frossard
patent: 4800159 (1989-01-01), Mullis
patent: 4801531 (1989-01-01), Frossard
Maniatis et al, Molecular Cloning: A Laboratory Manual (1982), pp. 230-234.
Lardegren et al, Science, v. 241, pp. 1077-80 (Aug. 1980).
Hickstein et al, Blood 70:89a (1987).
Burk et al, Nucleic Acids Research, vol. 16, N. 14, 1988 p. 7216.
Newman et al, J. Clin. Invest. v. 82, pp. 739-743 (Aug. 1988).
Newman et al., "The Human Platelet Alloantigens PlA1 and PlA2 are associated with a Leucine etc.", J. Clin. Invest. 83:1778-1781 (1989).
Zucker, Scientific American 242:86 (1980).
Keiffer et al, Eur. J. Biochem 164:189 (1987).
Hickstein et al, Blood 70:89a (1987).
Handagama et al., J. Clin. Invest. 86:1364-1368 (1990).
Instructions to Authors J. Clin. Invest.
Newman et al., J. Clin. Invest. 82:73-743 (1988).
Rosa et al., Blood 72(2):593-600 (1988).
Burk et al, Nucleic Acids Research 16(4):7216 (1988).
Newman et al., Arteriosclerosis *(5): 723a-724a (1988).
Maniatis, T. et al; Molecular Cloning: A laboratory Manual (1982); pp. 188-209.
Cardullo, R. A. et al; Detection of Nucleic Acid Hybridization by Nonradiative Fluorescence Resonance Energy Transfer: Proc. Natl. Acad. Sci. USA (12/1988); vol. 85, pp. 8790-8794.
Landegren, U. et al; A Ligase-Mediated Gene Detection Technique; Science (8/1988); vol. 241, pp. 1077-1080.
Newman, P. J. et al; Enzymatic Amplicication of Platelet-Specific Messenger RNA Using the Polymerase Chain Reaction; J. Clin Invest. (8/88); vol. 82, pp. 739-743.
Todd, J. A. et al; A Molecular Basis for MHC Class II-Associated Autoimmunity; Science (5/1988); vol. 240, pp. 1003-1009.
Kogan, S. C. et al; An Improved Method for Prenatal Diagnosis of Genetic Diseases by Analysis of Amplified DNA Sequences; The New England Journal of Medicine (10/1987); vol. 317, No. 16, pp. 985-990.
Aster, R. H.; Platelet Antigen Systems.
Phillips, D. R. et al; The Platelet Membrane Glycoprotein IIb-IIIa Complex; The Journal of The American Society of Hematoloty (4/1988); vol. 71, No. 4, pp. 831-843.
Newman, P. J. et al; The Human Platelet Alloantigens, Pl.sup.A1 and Pl.sup.A2, Are Associated with a Leucine.sup.33 /Proline.sup.33 Amino Acid Polymorphism in Membrane Glycoprotein IIIa, and Are Distinguishable by DNA Typing; J. Clin. Invest. (5/1989); vol. 83, pp. 1778-1781.
Aster Richard H.
Newman Peter J.
Fleisher Mindy B.
The Blood Center of Southeastern Wisconsin, Inc.
Wax Robert A.
LandOfFree
Polymorphism of human platelet membrane glycoprotein IIIa and di does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Polymorphism of human platelet membrane glycoprotein IIIa and di, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polymorphism of human platelet membrane glycoprotein IIIa and di will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1892473